Literature DB >> 8157445

Live attenuated vaccine vectors.

J J Mekalanos1.   

Abstract

Several different live attenuated vaccine vectors currently are under development. These vaccines are composed of living viruses or bacteria that are innocuous to the host but can replicate in host tissues and induce immune responses. The genes encoding foreign antigens can be inserted into these vectors to produce multivalent vaccines that promise to induce immunity to more than one target disease after the administration of a single dose of vaccine.

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Year:  1994        PMID: 8157445     DOI: 10.1017/s0266462300014057

Source DB:  PubMed          Journal:  Int J Technol Assess Health Care        ISSN: 0266-4623            Impact factor:   2.188


  3 in total

1.  Alterations in Vibrio cholerae motility phenotypes correlate with changes in virulence factor expression.

Authors:  C L Gardel; J J Mekalanos
Journal:  Infect Immun       Date:  1996-06       Impact factor: 3.441

2.  The live attenuated Actinobacillus pleuropneumoniae triple-deletion mutant ΔapxIC ΔapxIIC ΔapxIV-ORF1 strain, SLW05, Immunizes pigs against lethal challenge with Haemophilus parasuis.

Authors:  Shulin Fu; Jiwen Ou; Minmin Zhang; Juan Xu; Huazhen Liu; Jinlin Liu; Fangyan Yuan; Huanchun Chen; Weicheng Bei
Journal:  Clin Vaccine Immunol       Date:  2012-12-05

3.  Formulation and delivery of vaccines: Ongoing challenges for animal management.

Authors:  Sameer Sharma; Lyn A Hinds
Journal:  J Pharm Bioallied Sci       Date:  2012-10
  3 in total

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