[Effect of Rhodobryum roseum on hemorheology following acute coronary occlusion in dogs].

Following acute occlusion of the left anterior descending coronary artery, the significant and constant hemorheologic changes were observed in venous blood from ischemic area. 30 min after occlusion, the high shear rate (r = 230s-1), middle shear rate (r = 23s-1) and low shear rate (r = 5.75s-1), viscosity of whole blood (eta b) increased significantly, and this change occurred in viscosity of plasma (eta p) and in red cell electrophoretic time (RCET) also. These increases continued thereafter. In another group of dogs, 30 min after coronary occlusion, rapid dripping was performed with Rhodobryum roseum (Huixincao) injection from right femoral vein. After 10 min, eta b at all shear rate reduced significantly, and this reduction was observed in eta p and in RCET also. These findings suggested that the hyperviscosity syndrome developed in acute myocardial ischemic could be blocked by Hui Xin Cao.