Literature DB >> 8155669

Distribution of phospholipid hydroperoxide glutathione peroxidase (PHGPx) in rat testis mitochondria.

C Godeas1, G Sandri, E Panfili.   

Abstract

The distribution of phospholipid hydroperoxide glutathione peroxidase (PHGPx) in isolated rat testis mitochondria was investigated, using a reverse sucrose density gradient centrifugation procedure for the separation of the inner and outer membranes and the contact sites between the two membranes. The results indicate that PHGPx is largely localized in the contact sites fraction. This finding might therefore suggest that the enzyme has more than just an antioxidant function.

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Year:  1994        PMID： 8155669     DOI： 10.1016/0005-2736(94)90242-9

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  10 in total

1.  Mitochondrial respiratory chain-dependent generation of superoxide anion and its release into the intermembrane space.

Authors:  D Han; E Williams; E Cadenas
Journal:  Biochem J       Date:  2001-01-15       Impact factor: 3.857

2.  Mitochondrial oxidant stress triggers cell death in simulated ischemia-reperfusion.

Authors:  Gabriel Loor; Jyothisri Kondapalli; Hirotaro Iwase; Navdeep S Chandel; Gregory B Waypa; Robert D Guzy; Terry L Vanden Hoek; Paul T Schumacker
Journal:  Biochim Biophys Acta       Date:  2010-12-23

3.  Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis.

Authors:  K Nomura; H Imai; T Koumura; T Kobayashi; Y Nakagawa
Journal:  Biochem J       Date:  2000-10-01       Impact factor: 3.857

4.  Evidence for altered structure and impaired mitochondrial electron transport function in selenium deficiency.

Authors:  P Rani; K Lalitha
Journal:  Biol Trace Elem Res       Date:  1996-03       Impact factor: 3.738

5.  Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene.

Authors:  L A Esposito; J E Kokoszka; K G Waymire; B Cottrell; G R MacGregor; D C Wallace
Journal:  Free Radic Biol Med       Date:  2000-03-01       Impact factor: 7.376

6.  Protection from inactivation of the adenine nucleotide translocator during hypoglycaemia-induced apoptosis by mitochondrial phospholipid hydroperoxide glutathione peroxidase.

Authors:  Hirotaka Imai; Tomoko Koumura; Ryo Nakajima; Kazuhiro Nomura; Yasuhito Nakagawa
Journal:  Biochem J       Date:  2003-05-01       Impact factor: 3.857

7.  Phospholipid hydroperoxide glutathione peroxidase induces a delay in G1 of the cell cycle.

Authors:  Hong P Wang; Freya Q Schafer; Prabhat C Goswami; Larry W Oberley; Garry R Buettner
Journal:  Free Radic Res       Date:  2003-06

8.  Cloning, characterization, and expression analysis of goat (Capra hircus) phospholipid hydroperoxide glutathione peroxidase (PHGPx).

Authors:  Li-guang Shi; Wen-juan Xun; Wen-bin Yue; Chun-xiang Zhang; You-she Ren; Qian Wang; Xiao-ying Wu; Lei Shi; Ru-jie Yang; Fu-lin Lei
Journal:  Int J Biol Sci       Date:  2010-06-10       Impact factor: 6.580

9.  Analysis of age-associated changes in mitochondrial free radical generation by rat testis.

Authors:  Martha E Vázquez-Memije; Ruth Capin; Adela Tolosa; Mohammed El-Hafidi
Journal:  Mol Cell Biochem       Date:  2007-09-06       Impact factor: 3.396

10.  Reversal of mitochondrial proteomic loss in Type 1 diabetic heart with overexpression of phospholipid hydroperoxide glutathione peroxidase.

Authors:  Walter A Baseler; Erinne R Dabkowski; Rajaganapathi Jagannathan; Dharendra Thapa; Cody E Nichols; Danielle L Shepherd; Tara L Croston; Matthew Powell; Trust T Razunguzwa; Sara E Lewis; David M Schnell; John M Hollander
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2013-02-13       Impact factor: 3.619
  10 in total

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