Literature DB >> 8153339

Defecography in multiple sclerosis patients with severe constipation.

K P Gill1, Y W Chia, M M Henry, P J Shorvon.   

Abstract

PURPOSE: To evaluate defecography in assessment of anorectal function in patients with multiple sclerosis (MS) who have intractable constipation.
MATERIALS AND METHODS: Eleven patients with MS and constipation (10 women, one man) underwent defecography. A total of 130 mL of barium, liquid (20 mL) and paste, was introduced into the rectum. A dab of barium marked the external anal orifice, and, in the women, a tampon soaked with contrast medium marked the vagina. Video radiographic images and supplemental 100-mm static camera images were obtained.
RESULTS: During defecation, six patients had no puborectalis muscle effacement, four patients had partial effacement, and one patient had complete effacement. No rectal emptying occurred in five patients, and emptying was incomplete in the rest. Three patients developed an intussusception, and two developed a posterolateral pouch.
CONCLUSION: Defecography readily demonstrates rectal outlet obstruction and the failure of the puborectalis and anal sphincter muscles to relax. These are frequent findings in MS patients with intractable constipation.

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Year:  1994        PMID: 8153339     DOI: 10.1148/radiology.191.2.8153339

Source DB:  PubMed          Journal:  Radiology        ISSN: 0033-8419            Impact factor:   11.105


  10 in total

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2.  Modulation of the rectoanal inhibitory reflex (RAIR): qualitative and quantitative evaluation in multiple sclerosis.

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3.  Paradoxical puborectalis contraction and increased perineal descent.

Authors:  Ron G Landmann; Steven D Wexner
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Review 4.  Bladder, bowel and sexual dysfunction in multiple sclerosis: management strategies.

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5.  Paradoxical puborectalis contraction is a feature of constipation in patients with multiple sclerosis.

Authors:  Y W Chia; K P Gill; J S Jameson; A D Forti; M M Henry; M Swash; P J Shorvon
Journal:  J Neurol Neurosurg Psychiatry       Date:  1996-01       Impact factor: 10.154

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7.  A rare condition of anorectal dysfunction in a patient with multiple sclerosis: Coexistence of faecal incontinence and mechanical constipation: Report of case.

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9.  Gut dysfunction in patients with multiple sclerosis and the role of spinal cord involvement in the disease.

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Review 10.  Latitude, Vitamin D, Melatonin, and Gut Microbiota Act in Concert to Initiate Multiple Sclerosis: A New Mechanistic Pathway.

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  10 in total

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