Literature DB >> 8153134

The influence of thyroxine and propyl thiouracil on Parastrongylus malaysiensis infection in rats.

A B Kamis1, R A Ahmad, J S Chang, S Ambu.   

Abstract

Daily intramuscular injection with thyroxine (T4) at a dose of 2.5 micrograms/100 g body weight decreased the larvae and adult worm burden of Parastrongylus malaysiensis in the brain and pulmonary arteries of male Sprague-Dawley albino rats. In contrast, rats treated with propyl thiouracil (PTU), an antithyroid drug, at a dose of 3.75 mg/100 g body weight retained greater numbers of larvae and adult worms. The results may reflect the contrasting immunomodulatory effects of T4 and PTU that influence the susceptibility of the host.

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Year:  1994        PMID： 8153134     DOI： 10.1007/bf00932632

Source DB:  PubMed          Journal:  Parasitol Res        ISSN： 0932-0113            Impact factor:   2.289


  7 in total

1.  The effects of antithyroid drugs on intercellular mediators.

Authors:  R Wilson; J H McKillop; M Travers; J Smith; E Smith; J A Thomson
Journal:  Acta Endocrinol (Copenh)       Date:  1990-05

2.  Effects of thyroxine and thiouracil on the retention, growth and egg production of Microphallus pygmaeus in mice.

Authors:  R A Ahmad; B L James; A B Kamis
Journal:  Int J Parasitol       Date:  1986-10       Impact factor: 3.981

3.  Effect of thyroxine on immune response in C57Bl/6J mice.

Authors:  M K Gupta; T Chiang; S D Deodhar
Journal:  Acta Endocrinol (Copenh)       Date:  1983-05

4.  The influence of thyroxine on the host-parasite relationship of Ancylostoma caninum in Swiss albino mice.

Authors:  I Bhai; A K Pandey
Journal:  Int J Parasitol       Date:  1981-10       Impact factor: 3.981

5.  Effects of host endocrine gland removal on the permissive status of laboratory rodents to infection by Schistosoma mansoni.

Authors:  P M Knopf; M Soliman
Journal:  Int J Parasitol       Date:  1980-06       Impact factor: 3.981

6.  Systematics of species referred to the genus Angiostrongylus.

Authors:  J E Ubelaker
Journal:  J Parasitol       Date:  1986-04       Impact factor: 1.276

7.  Worm burden and leukocyte response in Angiostrongylus malaysiensis-infected rats: the influence of testosterone.

Authors:  A B Kamis; R A Ahmad; M Z Badrul-Munir
Journal:  Parasitol Res       Date:  1992       Impact factor: 2.289
  7 in total

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