Literature DB >> 8152776

The use of botulinum toxin for treatment of acquired nystagmus and oscillopsia.

S T Ruben1, J P Lee, D O'Neil, I Dunlop, J S Elston.   

Abstract

PURPOSE: To evaluate the role of botulinum toxin A (BTA) in treating patients with diminished visual acuity secondary to acquired nystagmus and oscillopsia.
METHODS: Twelve patients with acquired nystagmus causing oscillopsia and reduced vision were treated with injection of BTA. Botulinum toxin A was injected directly into the horizontal recti in three patients, and in nine patients retrobulbar BTA was administered. Injections were given at 3- to 4-month intervals and repeated as long as patients noted improvement in their quality of life.
RESULTS: Improvement in visual function varied, and not all patients benefited from the procedure. However, 8 of 12 patients demonstrated a measurable improvement in visual acuity. Transient ptosis was the most common side effect.
CONCLUSION: Retrobulbar BTA provides a simple and safe alternative in managing a condition for which alternative treatments are typically unsatisfactory.

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Year:  1994        PMID: 8152776     DOI: 10.1016/s0161-6420(94)31265-6

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  5 in total

Review 1.  Medical treatment of nystagmus and its visual consequences.

Authors:  John S Stahl; Gordon T Plant; R John Leigh
Journal:  J R Soc Med       Date:  2002-05       Impact factor: 5.344

2.  Botulinum toxin treatment of "one and a half syndrome".

Authors:  A Kipioti; R H Taylor
Journal:  Br J Ophthalmol       Date:  2003-07       Impact factor: 4.638

Review 3.  The role of drug treatment in children with strabismus and amblyopia.

Authors:  K I Chatzistefanou; M D Mills
Journal:  Paediatr Drugs       Date:  2000 Mar-Apr       Impact factor: 3.930

4.  Treatment of Nystagmus in Brainstem Cavernous Malformation with Botulinum Toxin.

Authors:  Yi-Ren Chen; Douglas Fredrick; Gary K Steinberg; Yaping J Liao
Journal:  Cureus       Date:  2016-04-01

5.  The Use of Botulinum Toxin in a Case of Acquired Periodic Alternating Nystagmus.

Authors:  Nadia Venturi; Gillian Adams; Maria Theodorou
Journal:  Br Ir Orthopt J       Date:  2021-04-15
  5 in total

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