Literature DB >> 8149726

The use of clozapine in borderline-intellectual-functioning and mentally retarded schizophrenic patients.

M Sajatovic1, L F Ramirez, J T Kenny, H Y Meltzer.   

Abstract

The effect of clozapine, an atypical antipsychotic medication, in five patients with treatment-resistant schizophrenia or schizoaffective disorder and borderline intellectual functioning or mental retardation (MR) was studied. Four of the five patients responded favorably to clozapine with few side effects. Progressive improvement in psychopathology, social functioning, and ability to participate in daily activities were noted.

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Year:  1994        PMID： 8149726     DOI： 10.1016/0010-440x(94)90166-x

Source DB:  PubMed          Journal:  Compr Psychiatry        ISSN： 0010-440X            Impact factor:   3.735


  4 in total

1.  Brief report: effects of clozapine on self-injurious behavior of two risperidone nonresponders with mental retardation.

Authors:  R Hammock; W R Levine; S R Schroeder
Journal:  J Autism Dev Disord       Date:  2001-02

Review 2.  Pharmacotherapy of disorders in mental retardation.

Authors:  M G Aman; A Collier-Crespin; R L Lindsay
Journal:  Eur Child Adolesc Psychiatry       Date:  2000       Impact factor: 4.785

Review 3.  Clozapine for psychotic disorders in adults with intellectual disabilities.

Authors:  Muhammad Ayub; Khalid Saeed; Tariq A Munshi; Farooq Naeem
Journal:  Cochrane Database Syst Rev       Date:  2015-09-23

4.  Effect of Intravenous Lipid Emulsion on Clozapine Acute Toxicity in Rats.

Authors:  Bahareh Sadat Yousefsani; Seyed Ahmad Mohajeri; Mohammad Moshiri; Amir Hossein Jafarian; Hossein Hosseinzadeh
Journal:  J Pharmacopuncture       Date:  2019-09-30
  4 in total

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