Literature DB >> 814893

A genetic marker in the variable region of rabbit immunoglobulin heavy chain.

L R Mole.   

Abstract

A previous study [Mole et al. (1971) Biochem. J. 124, 301-318] showed several differences in sequence between the variable (V) regions of rabbit immunoglobulin Aa1 and Aa3 heavy chains. The inheritance of one such difference has been followed in a family of 38 rabbits by a radioautographic peptide-'map' technique and is shown to segregate in a Mendelian fashion. This clearly demonstrates the presence of a genetic marker in the rabbit heavy-chain V region, although the finding that Aa2 and Aa3 heavy chains have identity of sequence in the region studied obscures the relationship of this genetic marker to the a locus.

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Year:  1975        PMID: 814893      PMCID: PMC1172365          DOI: 10.1042/bj1510351

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  26 in total

1.  Sequence studies on the constant region of the Fd sections of rabbit immunoglobulin G of different allotype.

Authors:  D M Pratt; L E Mole
Journal:  Biochem J       Date:  1975-11       Impact factor: 3.857

2.  A rabbit with the allotypic phenotype: ala2a3 b4b5b6.

Authors:  A D Strosberg; C Hamers-Casterman; W Van der Loo; R Hamers
Journal:  J Immunol       Date:  1974-10       Impact factor: 5.422

3.  Identification and genetic control of allotypic specificities on two variable region subgroups of rabbit immunoglobulin heavy chains.

Authors:  B S Kim; S Dray
Journal:  Eur J Immunol       Date:  1972-12       Impact factor: 5.532

4.  Serologic identity of the b4 allotypic determinants present on homogeneous rabbit light chains with different N-terminal amino acid sequences.

Authors:  T J Kindt; R K Seide; H Lackland; A L Thunberg
Journal:  J Immunol       Date:  1972-10       Impact factor: 5.422

Review 5.  Genetic control of H chain biosynthesis in the rabbit.

Authors:  C W Todd
Journal:  Fed Proc       Date:  1972 Jan-Feb

Review 6.  The search for antibodies with molecular uniformity.

Authors:  R M Krause
Journal:  Adv Immunol       Date:  1970       Impact factor: 3.543

7.  Restricted rabbit antibodies: amino acid sequences of rabbit H chains of allotype a1, a2, and a3 in the region 80 to 94.

Authors:  J C Jaton; D G Braun; A D Strosberg; E Haber; J E Morris
Journal:  J Immunol       Date:  1973-12       Impact factor: 5.422

8.  Partial amino acid sequence in the N-terminal region of an anti-pneumococcal immunoglobulin heavy chain of allotype alpha2.

Authors:  J C Jaton; J Haimovich
Journal:  Biochem J       Date:  1974-04       Impact factor: 3.857

9.  Diverse expression of group a allotype specificities on the heavy chains of homogeneous rabbit antibodies.

Authors:  T J Kindt; R K Seide; B F Tack; C W Todd
Journal:  J Exp Med       Date:  1973-07-01       Impact factor: 14.307

10.  An idiotypic cross-reaction between allotype a3 and allotype a negative rabbit antibodies to streptococcal carbohydrate.

Authors:  T J Kindt; D G Klapper; M D Waterfield
Journal:  J Exp Med       Date:  1973-03-01       Impact factor: 14.307

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  6 in total

1.  Sequence studies on the constant region of the Fd sections of rabbit immunoglobulin G of different allotype.

Authors:  D M Pratt; L E Mole
Journal:  Biochem J       Date:  1975-11       Impact factor: 3.857

2.  Sequence studies on the heavy chain of rabbit immunoglobulin A of different alpha-locus allotypes.

Authors:  A P Johnstone; L E Mole
Journal:  Biochem J       Date:  1977-10-01       Impact factor: 3.857

3.  Analysis of HLA-DR polymorphism by two-dimensional peptide mapping.

Authors:  G Corte; G Damiani; F Calabi; M Fabbi; A Bargellesi
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205

4.  Distinct forms of both alpha and beta subunits are present in the human Ia molecular pool.

Authors:  R S Accolla; N Gross; S Carrel; G Corte
Journal:  Proc Natl Acad Sci U S A       Date:  1981-07       Impact factor: 11.205

5.  Localization and biosynthesis of NADH-cytochrome b5 reductase, an integral membrane protein, in rat liver cells. II. Evidence that a single enzyme accounts for the activity in its various subcellular locations.

Authors:  J Meldolesi; G Corte; G Pietrini; N Borgese
Journal:  J Cell Biol       Date:  1980-06       Impact factor: 10.539

6.  Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells.

Authors:  Franca Gerosa; Barbara Baldani-Guerra; Lyudmila A Lyakh; Giovanna Batoni; Semih Esin; Robin T Winkler-Pickett; Maria Rita Consolaro; Mario De Marchi; Daniela Giachino; Angela Robbiano; Marco Astegiano; Angela Sambataro; Robert A Kastelein; Giuseppe Carra; Giorgio Trinchieri
Journal:  J Exp Med       Date:  2008-05-19       Impact factor: 14.307

  6 in total

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