Literature DB >> 8148614

Cadmium in blood in Alzheimer's disease and non-demented subjects: results from a population-based study.

H Basun1, B Lind, M Nordberg, M Nordström, K S Björkstén, B Winblad.   

Abstract

Blood cadmium concentrations were studied in Alzheimer's disease (AD) and non-demented subjects. The 29 individuals were randomized from the ongoing population survey on ageing and dementia in Stockholm, the Kungsholmen Project. Smokers had, as expected, higher cadmium levels than non-smokers. Cadmium concentrations in blood were related to diastolic blood pressure in non-smoking, non-demented individuals. In contrast to previous reports no differences in blood cadmium levels were found between AD sufferers and non-demented subjects. Furthermore, there were no correlations between cadmium levels in blood and age or cognitive functions. The importance of quality assurance in sample collection and analysis of cadmium as well as scrutinizing smoking habits is emphasized.

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Year:  1994        PMID： 8148614     DOI： 10.1007/bf00140482

Source DB:  PubMed          Journal:  Biometals        ISSN： 0966-0844            Impact factor:   2.949


  18 in total

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3.  A kinetic model of cadmium metabolism in the human being.

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4.  Cadmium, chromium, and cardiovascular disease.

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5.  Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease.

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Journal:  Nature       Date:  1991-02-21       Impact factor: 49.962

6.  Occurrence of dementia in advanced age: the study design of the Kungsholmen Project.

Authors:  L Fratiglioni; M Viitanen; L Bäckman; P O Sandman; B Winblad
Journal:  Neuroepidemiology       Date:  1992       Impact factor: 3.282

7.  Metals and the liver in Alzheimer's disease. An investigation of hepatic zinc, copper, cadmium, and metallothionein.

Authors:  E Lui; M Fisman; C Wong; F Diaz
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8.  CAMDEX. A standardised instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia.

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9.  A case-referent study on neuropsychiatric disorders among workers exposed to solvents.

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Journal:  Scand J Work Environ Health       Date:  1976-03       Impact factor: 5.024

10.  Prevalence of Alzheimer's disease and other dementias in an elderly urban population: relationship with age, sex, and education.

Authors:  L Fratiglioni; M Grut; Y Forsell; M Viitanen; M Grafström; K Holmén; K Ericsson; L Bäckman; A Ahlbom; B Winblad
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  9 in total

1.  Metallothionein gene expression in peripheral lymphocytes from cadmium-exposed workers.

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Journal:  Cell Stress Chaperones       Date:  2001-04       Impact factor: 3.667

2.  Cadmium and Alzheimer's disease mortality in U.S. adults: Updated evidence with a urinary biomarker and extended follow-up time.

Authors:  Qing Peng; Kelly M Bakulski; Bin Nan; Sung Kyun Park
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3.  A system-based comparison of gene expression reveals alterations in oxidative stress, disruption of ubiquitin-proteasome system and altered cell cycle regulation after exposure to cadmium and methylmercury in mouse embryonic fibroblast.

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Review 4.  Heavy Metals Exposure and Alzheimer's Disease and Related Dementias.

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5.  Trace element levels and cognitive function in rural elderly Chinese.

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Journal:  J Gerontol A Biol Sci Med Sci       Date:  2008-06       Impact factor: 6.053

6.  Alzheimer's disease and cigarette smoke components: effects of nicotine, PAHs, and Cd(II), Cr(III), Pb(II), Pb(IV) ions on amyloid-β peptide aggregation.

Authors:  Cecilia Wallin; Sabrina B Sholts; Nicklas Österlund; Jinghui Luo; Jüri Jarvet; Per M Roos; Leopold Ilag; Astrid Gräslund; Sebastian K T S Wärmländer
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7.  Associations between blood cadmium levels and cognitive function in a cross-sectional study of US adults aged 60 years or older.

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Review 9.  Biometal Dyshomeostasis and Toxic Metal Accumulations in the Development of Alzheimer's Disease.

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  9 in total

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