Literature DB >> 8148413

Reduced-system analysis of the effects of serotonin on a molluscan burster neuron.

R Bertram1.   

Abstract

The mathematical model described in Bertram (1993) is used to carry out a detailed examination of the manner in which the neurotransmitter serotonin modifies the voltage waveform generated endogenously by burster neuron R15 of Aplysia. This analysis makes use of a reduced system of equations, taking advantage of the slow rate of change of a pair of system variables relative to the others. Such analysis also yields information concerning the sensitivity of the neuron to brief+ synaptic perturbations.

Entities:  

Mesh:

Substances:

Year:  1994        PMID: 8148413     DOI: 10.1007/bf00200333

Source DB:  PubMed          Journal:  Biol Cybern        ISSN: 0340-1200            Impact factor:   2.086


  15 in total

1.  Augmentation of bursting pacemaker activity by egg-laying hormone in Aplysia neuron R15 is mediated by a cyclic AMP-dependent increase in Ca2+ and K+ currents.

Authors:  E S Levitan; R H Kramer; I B Levitan
Journal:  Proc Natl Acad Sci U S A       Date:  1987-09       Impact factor: 11.205

2.  Simulation of the bursting activity of neuron R15 in Aplysia: role of ionic currents, calcium balance, and modulatory transmitters.

Authors:  C C Canavier; J W Clark; J H Byrne
Journal:  J Neurophysiol       Date:  1991-12       Impact factor: 2.714

3.  Calcium and delayed potassium currents in mouse pancreatic beta-cells under voltage-clamp conditions.

Authors:  P Rorsman; G Trube
Journal:  J Physiol       Date:  1986-05       Impact factor: 5.182

4.  Serotonin acting via cyclic AMP enhances both the hyperpolarizing and depolarizing phases of bursting pacemaker activity in the Aplysia neuron R15.

Authors:  E S Levitan; I B Levitan
Journal:  J Neurosci       Date:  1988-04       Impact factor: 6.167

5.  Dissection of a model for neuronal parabolic bursting.

Authors:  J Rinzel; Y S Lee
Journal:  J Math Biol       Date:  1987       Impact factor: 2.259

6.  From simple to complex oscillatory behaviour: analysis of bursting in a multiply regulated biochemical system.

Authors:  O Decroly; A Goldbeter
Journal:  J Theor Biol       Date:  1987-01-21       Impact factor: 2.691

7.  Calcium-dependent inward current in Aplysia bursting pace-maker neurones.

Authors:  R H Kramer; R S Zucker
Journal:  J Physiol       Date:  1985-05       Impact factor: 5.182

8.  Calcium-induced inactivation of calcium current causes the inter-burst hyperpolarization of Aplysia bursting neurones.

Authors:  R H Kramer; R S Zucker
Journal:  J Physiol       Date:  1985-05       Impact factor: 5.182

9.  The effects of calcium++ on bursting neurons. A modeling study.

Authors:  R E Plant
Journal:  Biophys J       Date:  1978-03       Impact factor: 4.033

10.  Fine tuning of neuronal electrical activity: modulation of several ion channels by intracellular messengers in a single identified nerve cell.

Authors:  D P Lotshaw; E S Levitan; I B Levitan
Journal:  J Exp Biol       Date:  1986-09       Impact factor: 3.312

View more
  9 in total

1.  Mechanism, dynamics, and biological existence of multistability in a large class of bursting neurons.

Authors:  Jonathan P Newman; Robert J Butera
Journal:  Chaos       Date:  2010-06       Impact factor: 3.642

2.  A modeling comparison of projection neuron- and neuromodulator-elicited oscillations in a central pattern generating network.

Authors:  Nickolas Kintos; Michael P Nusbaum; Farzan Nadim
Journal:  J Comput Neurosci       Date:  2007-11-29       Impact factor: 1.621

3.  Relationship between burst properties and sensitivity to input: a theoretical analysis.

Authors:  E Sivan; H Parnas; D Dolev
Journal:  J Comput Neurosci       Date:  1996-03       Impact factor: 1.621

4.  Two types of burst firing in gonadotrophin-releasing hormone neurones.

Authors:  Z Chu; M Tomaiuolo; R Bertram; S M Moenter
Journal:  J Neuroendocrinol       Date:  2012-07       Impact factor: 3.627

5.  Topological and phenomenological classification of bursting oscillations.

Authors:  R Bertram; M J Butte; T Kiemel; A Sherman
Journal:  Bull Math Biol       Date:  1995-05       Impact factor: 1.758

6.  Analysis of the effects of modulatory agents on a modeled bursting neuron: dynamic interactions between voltage and calcium dependent systems.

Authors:  R J Butera; J W Clark; C C Canavier; D A Baxter; J H Byrne
Journal:  J Comput Neurosci       Date:  1995-03       Impact factor: 1.621

7.  Bifurcations of emergent bursting in a neuronal network.

Authors:  Yu Wu; Wenlian Lu; Wei Lin; Gareth Leng; Jianfeng Feng
Journal:  PLoS One       Date:  2012-06-07       Impact factor: 3.240

Review 8.  Toward a multiscale modeling framework for understanding serotonergic function.

Authors:  KongFatt Wong-Lin; Da-Hui Wang; Ahmed A Moustafa; Jeremiah Y Cohen; Kae Nakamura
Journal:  J Psychopharmacol       Date:  2017-04-18       Impact factor: 4.153

9.  Temperature-dependent bursting pattern analysis by modified Plant model.

Authors:  Nam Gyu Hyun; Kwang-Ho Hyun; Kwang-Beom Hyun; Kyungmin Lee
Journal:  Mol Brain       Date:  2014-07-22       Impact factor: 4.041

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.