Literature DB >> 8148383

Sequencing of a cDNA encoding the human fast-twitch skeletal muscle isoform of troponin I.

L Zhu1, G Perez-Alvarado, R Wade.   

Abstract

A cDNA encoding the human fast-twitch skeletal muscle isoform of troponin I (TnIfast) has been sequenced. This cDNA is 701 base pairs in length, and encodes a protein of 182 amino acids. TnIfast is the last of the three known human TnI isoforms to be sequenced. Comparison of the deduced human TnIfast protein sequence with a variety of troponin I isoforms from other species has revealed a high degree of cross-species sequence conservation between TnIfast proteins.

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Year:  1994        PMID： 8148383     DOI： 10.1016/0167-4781(94)90297-6

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  4 in total

1.  A polypeptide from shark troponin I can inhibit angiogenesis and tumor growth.

Authors:  Qiuling Xie; Sheng Yao; Xiaojia Chen; Lihui Xu; Wendan Peng; Ling Zhang; Qihao Zhang; Xu-Fang Liang; An Hong
Journal:  Mol Biol Rep       Date:  2011-07-13       Impact factor: 2.316

2.  Strong evolutionary conservation of broadly expressed protein isoforms in the troponin I gene family and other vertebrate gene families.

Authors:  K E Hastings
Journal:  J Mol Evol       Date:  1996-06       Impact factor: 2.395

3.  Troponin I is present in human cartilage and inhibits angiogenesis.

Authors:  M A Moses; D Wiederschain; I Wu; C A Fernandez; V Ghazizadeh; W S Lane; E Flynn; A Sytkowski; T Tao; R Langer
Journal:  Proc Natl Acad Sci U S A       Date:  1999-03-16       Impact factor: 11.205

4.  Cloning of a newly identified heart-specific troponin I isoform, which lacks the troponin T binding portion, using the yeast hybrid system.

Authors:  Hideaki Suzuki; Yasuhiro Arakawa; Masaki Ito; Hisashi Yamada; Junko Horiguchi-Yamada
Journal:  Exp Clin Cardiol       Date:  2006
  4 in total

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