Literature DB >> 8146742

Development of post-traumatic cysts in the spinal cord of rats-subjected to severe spinal cord contusion.

G Guizar-Sahagun1, I Grijalva, I Madrazo, R Franco-Bourland, H Salgado, A Ibarra, E Oliva, A Zepeda.   

Abstract

To study the development of post-traumatic spinal cord (SC) cysts, and their fine anatomic characteristics, rats were subjected to severe SC contusion. Specimens were analyzed from day 1 to 1 year post-injury. Using conventional light, and transmission and scanning electron microscopy, three stages were typified, namely: necrosis, repair, and stability. The final cell composition and thickness of the cyst walls were not uniform. Astrocytes, fibroblasts, ependymal cells, and collagen fibers were the main constituents. Chronic inflammatory cells were also observed. The neuropathologic characterization of posttraumatic SC cysts could be useful in planning strategies for SC reconstruction at different times post-injury.

Entities:  

Mesh:

Year:  1994        PMID: 8146742     DOI: 10.1016/0090-3019(94)90131-7

Source DB:  PubMed          Journal:  Surg Neurol        ISSN: 0090-3019


  10 in total

1.  Transduced Schwann cells promote axon growth and myelination after spinal cord injury.

Authors:  Kevin L Golden; Damien D Pearse; Bas Blits; Maneesh S Garg; Martin Oudega; Patrick M Wood; Mary Bartlett Bunge
Journal:  Exp Neurol       Date:  2007-07-13       Impact factor: 5.330

2.  Diffusion-weighted MR imaging in a rat model of syringomyelia after excitotoxic spinal cord injury.

Authors:  E D Schwartz; R P Yezierski; P M Pattany; R M Quencer; R G Weaver
Journal:  AJNR Am J Neuroradiol       Date:  1999-09       Impact factor: 3.825

3.  Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment.

Authors:  Kevin D Beck; Hal X Nguyen; Manuel D Galvan; Desirée L Salazar; Trent M Woodruff; Aileen J Anderson
Journal:  Brain       Date:  2010-01-19       Impact factor: 13.501

Review 4.  Combinatorial strategies with Schwann cell transplantation to improve repair of the injured spinal cord.

Authors:  Jenny Fortun; Caitlin E Hill; Mary Bartlett Bunge
Journal:  Neurosci Lett       Date:  2009-01-17       Impact factor: 3.046

5.  Amitriptyline pharmacokinetics in experimental spinal cord injury in the rabbit.

Authors:  H Reihanikermani; M Ansari; A Soltani; M S Meymandi
Journal:  Indian J Pharm Sci       Date:  2008-11       Impact factor: 0.975

6.  The roads to mitochondrial dysfunction in a rat model of posttraumatic syringomyelia.

Authors:  Zhiqiang Hu; Jian Tu
Journal:  Biomed Res Int       Date:  2015-01-13       Impact factor: 3.411

7.  Precise Delivery Into Chronic Spinal Cord Injury Syringomyelic Cysts with Magnetic Nanoparticles MRI Visualization.

Authors:  Chao Zhang; Anna Y Morozova; Maxim A Abakumov; Ilya L Gubsky; Patricia Douglas; Shiqing Feng; Andrey S Bryukhovetskiy; Vladimir P Chekhonin
Journal:  Med Sci Monit       Date:  2015-10-21

Review 8.  Biomaterials for Local, Controlled Drug Delivery to the Injured Spinal Cord.

Authors:  Alexis M Ziemba; Ryan J Gilbert
Journal:  Front Pharmacol       Date:  2017-05-10       Impact factor: 5.810

9.  Use of a Combination Strategy to Improve Morphological and Functional Recovery in Rats With Chronic Spinal Cord Injury.

Authors:  Roxana Rodríguez-Barrera; Adrián Flores-Romero; Vinnitsa Buzoianu-Anguiano; Elisa Garcia; Karla Soria-Zavala; Diego Incontri-Abraham; Marcela Garibay-López; Juan José Juárez-Vignon Whaley; Antonio Ibarra
Journal:  Front Neurol       Date:  2020-04-02       Impact factor: 4.003

10.  Long-term production of BDNF and NT-3 induced by A91-immunization after spinal cord injury.

Authors:  Susana Martiñón; Elisa García-Vences; Diana Toscano-Tejeida; Adrian Flores-Romero; Roxana Rodriguez-Barrera; Manuel Ferrusquia; Rolando E Hernández-Muñoz; Antonio Ibarra
Journal:  BMC Neurosci       Date:  2016-06-30       Impact factor: 3.288

  10 in total

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