Literature DB >> 8146236

The Croonian Lecture, 1993. The endothelium: maestro of the blood circulation.

J R Vane1.   

Abstract

The vascular endothelium plays a vital role in the control of the circulation. It metabolizes various vasoactive substances, coverts angiotensin I to angiotensin II and secretes the potent vasodilators prostacyclin and EDRF (NO) and the vasoconstrictor peptide endothelin-1. The balance between these mediators determines the responses of the cardiovascular system in diseases such as hypertension, atherosclerosis and myocardial infarction.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 8146236     DOI： 10.1098/rstb.1994.0023

Source DB:  PubMed          Journal:  Philos Trans R Soc Lond B Biol Sci        ISSN： 0962-8436            Impact factor:   6.237


  19 in total

1.  Effects of S-ethylisothiourea, a potent inhibitor of nitric oxide synthase, alone or in combination with a nitric oxide donor in splanchnic artery occlusion shock.

Authors:  F Squadrito; D Altavilla; G Squadrito; G M Campo; M Ioculano; P Canale; F Rossi; A Saitta; A P Caputi
Journal:  Br J Pharmacol       Date:  1996-09       Impact factor: 8.739

Review 2.  The Second Gaddum Lecture: its origins and outcomes.

Authors:  Y S Bakhle
Journal:  Br J Pharmacol       Date:  2020-02-05       Impact factor: 8.739

3.  Blockade of the purinergic P2Y12 receptor greatly increases the platelet inhibitory actions of nitric oxide.

Authors:  Nicholas S Kirkby; Martina H Lundberg; Melissa V Chan; Ivana Vojnovic; Antonia B Solomon; Michael Emerson; Jane A Mitchell; Timothy D Warner
Journal:  Proc Natl Acad Sci U S A       Date:  2013-09-03       Impact factor: 11.205

Review 4.  Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis.

Authors:  Michael A Gimbrone; Guillermo García-Cardeña
Journal:  Circ Res       Date:  2016-02-19       Impact factor: 17.367

5.  DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite.

Authors:  C Szabó; B Zingarelli; M O'Connor; A L Salzman
Journal:  Proc Natl Acad Sci U S A       Date:  1996-03-05       Impact factor: 11.205

6.  Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform.

Authors:  G J Southan; B Zingarelli; M O'Connor; A L Salzman; C Szabó
Journal:  Br J Pharmacol       Date:  1996-02       Impact factor: 8.739

7.  Gi proteins and the response to 5-hydroxytryptamine in porcine cultured endothelial cells with impaired release of EDRF.

Authors:  N S Day; T Ge; J Codina; L Birnbaumer; P M Vanhoutte; C M Boulanger
Journal:  Br J Pharmacol       Date:  1995-07       Impact factor: 8.739

8.  Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity.

Authors:  G J Southan; C Szabó; C Thiemermann
Journal:  Br J Pharmacol       Date:  1995-01       Impact factor: 8.739

9.  Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase.

Authors:  C Szabó; G J Southan; C Thiemermann
Journal:  Proc Natl Acad Sci U S A       Date:  1994-12-20       Impact factor: 11.205

Review 10.  EDHF: spreading the influence of the endothelium.

Authors:  Christopher J Garland; C Robin Hiley; Kim A Dora
Journal:  Br J Pharmacol       Date:  2011-10       Impact factor: 8.739
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.