Literature DB >> 8145219

High-affinity and potent, water-soluble 5-amino-1,4-benzodiazepine CCKB/gastrin receptor antagonists containing a cationic solubilizing group.

G A Showell1, S Bourrain, J G Neduvelil, S R Fletcher, R Baker, A P Watt, A E Fletcher, S B Freedman, J A Kemp, G R Marshall.   

Abstract

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Year:  1994        PMID： 8145219     DOI： 10.1021/jm00032a002

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  6 in total

1.  Identification of a series of CCK-2 receptor nonpeptide agonists: sensitivity to stereochemistry and a receptor point mutation.

Authors:  Alan S Kopin; Edward W McBride; Ci Chen; Roger M Freidinger; Duan Chen; Chun-Mei Zhao; Martin Beinborn
Journal:  Proc Natl Acad Sci U S A       Date:  2003-04-15       Impact factor: 11.205

2.  Inter- and intraspecies polymorphisms in the cholecystokinin-B/gastrin receptor alter drug efficacy.

Authors:  A S Kopin; E W McBride; M C Gordon; S M Quinn; M Beinborn
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-30       Impact factor: 11.205

3.  Cholecystokinin and psychiatric disorders : role in aetiology and potential of receptor antagonists in therapy.

Authors:  J Shlik; E Vasar; J Bradwejn
Journal:  CNS Drugs       Date:  1997-08       Impact factor: 5.749

4.  Lack of effect of CCKB receptor antagonists in ethological and conditioned animal screens for anxiolytic drugs.

Authors:  G R Dawson; N M Rupniak; S D Iversen; R Curnow; S Tye; K J Stanhope; M D Tricklebank
Journal:  Psychopharmacology (Berl)       Date:  1995-09       Impact factor: 4.530

5.  Antidepressant/anxiolytic and anti-nociceptive effects of novel 2-substituted 1,4-benzodiazepine-2-ones.

Authors:  Harjit Singh; Jintana Sattayasai; Pornthip Lattmann; Yodchai Boonprakob; Eric Lattmann
Journal:  Sci Pharm       Date:  2010-05-17

Review 6.  CCKB/gastrin receptor antagonists: recent advances and potential uses in gastric secretory disorders.

Authors:  R T Jensen
Journal:  Yale J Biol Med       Date:  1996 May-Jun
  6 in total

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