Literature DB >> 8143137

Calmodulin-activated bacterial adenylate cyclases as virulence factors.

M Mock1, A Ullmann.   

Abstract

Bordetella pertussis and Bacillus anthracis each produce a virulence-associated, calmodulin-dependent adenylate cyclase toxin, which generates increased levels of cyclic AMP in eukaryotic cells. The two proteins share sequence similarities in their catalytic domains. The remaining regions display different structural and functional organizations that account for the differences both in interaction of the two toxins with target cells and in the resulting disease symptoms.

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Year:  1993        PMID： 8143137     DOI： 10.1016/0966-842x(93)90089-a

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  15 in total

1.  Delivery of CD8(+) T-cell epitopes into major histocompatibility complex class I antigen presentation pathway by Bordetella pertussis adenylate cyclase: delineation of cell invasive structures and permissive insertion sites.

Authors:  R Osicka; A Osicková; T Basar; P Guermonprez; M Rojas; C Leclerc; P Sebo
Journal:  Infect Immun       Date:  2000-01       Impact factor: 3.441

2.  Identification of a region that assists membrane insertion and translocation of the catalytic domain of Bordetella pertussis CyaA toxin.

Authors:  Johanna C Karst; Robert Barker; Usha Devi; Marcus J Swann; Marilyne Davi; Stephen J Roser; Daniel Ladant; Alexandre Chenal
Journal:  J Biol Chem       Date:  2012-01-12       Impact factor: 5.157

3.  Status of YopM and YopN in the Yersinia Yop virulon: YopM of Y.enterocolitica is internalized inside the cytosol of PU5-1.8 macrophages by the YopB, D, N delivery apparatus.

Authors:  A Boland; M P Sory; M Iriarte; C Kerbourch; P Wattiau; G R Cornelis
Journal:  EMBO J       Date:  1996-10-01       Impact factor: 11.598

4.  Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases.

Authors:  Petra Břehová; Markéta Šmídková; Jan Skácel; Martin Dračínský; Helena Mertlíková-Kaiserová; Monica P Soto Velasquez; Val J Watts; Zlatko Janeba
Journal:  ChemMedChem       Date:  2016-10-24       Impact factor: 3.466

5.  A bacterial two-hybrid system based on a reconstituted signal transduction pathway.

Authors:  G Karimova; J Pidoux; A Ullmann; D Ladant
Journal:  Proc Natl Acad Sci U S A       Date:  1998-05-12       Impact factor: 11.205

6.  Purification and characterization of a psychrophilic, calcium-induced, growth-phase-dependent metalloprotease from the fish pathogen Flavobacterium psychrophilum.

Authors:  P Secades; B Alvarez; J A Guijarro
Journal:  Appl Environ Microbiol       Date:  2001-06       Impact factor: 4.792

7.  Role of luxS in Bacillus anthracis growth and virulence factor expression.

Authors:  Marcus B Jones; Scott N Peterson; Rosslyn Benn; John C Braisted; Behnam Jarrahi; Kenneth Shatzkes; Dacheng Ren; Thomas K Wood; Martin J Blaser
Journal:  Virulence       Date:  2010 Mar-Apr       Impact factor: 5.882

8.  Anti-viral protection conferred by recombinant adenylate cyclase toxins from Bordetella pertussis carrying a CD8+ T cell epitope from lymphocytic choriomeningitis virus.

Authors:  M F Saron; C Fayolle; P Sebo; D Ladant; A Ullmann; C Leclerc
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-01       Impact factor: 11.205

9.  Protective immunity induced by Bacillus anthracis toxin-deficient strains.

Authors:  C Pezard; M Weber; J C Sirard; P Berche; M Mock
Journal:  Infect Immun       Date:  1995-04       Impact factor: 3.441

10.  Functional and structural characterization of chimeras of a bacterial genotoxin and human type I DNAse.

Authors:  Joseph M DiRienzo; Linsen Cao; Alla Volgina; Georges Bandelac; Jonathan Korostoff
Journal:  FEMS Microbiol Lett       Date:  2008-12-11       Impact factor: 2.742
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