| Literature DB >> 8141593 |
J M Crance1, F Lévêque, E Biziagos, H van Cuyck-Gandré, A Jouan, R Deloince.
Abstract
Glycyrrhizin (GL) achieved a concentration-dependent inhibition of the replication of hepatitis A virus (HAV) in PLC/PRF/5 cells. GL has been shown to inhibit an early stage of the HAV replication. GL was not virucidal and had no measurable effect on the adsorption of [3H]uridine-labelled virions to cells. GL inhibited HAV penetration of the plasma membrane as measured by the amount of infective virus no longer neutralizable by specific antibody over time.Entities:
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Year: 1994 PMID: 8141593 DOI: 10.1016/0166-3542(94)90033-7
Source DB: PubMed Journal: Antiviral Res ISSN: 0166-3542 Impact factor: 5.970