Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Characterization of a serotonin receptor endogenous to frog melanophores.

Literature DB >> 8139699

Characterization of a serotonin receptor endogenous to frog melanophores.

Abstract

The response of a cell line of Xenopus laevis melanophores to serotonin was examined. Serotonin increased intracellular levels of cAMP and induced pigment dispersion in the cells. The responses depended on both the concentration of serotonin applied and on the time for which the cells were exposed to serotonin. Using a recently described, microtiter-plate-based bioassay, a series of serotonin receptor ligands were evaluated as agonists or antagonists at the melanophore serotonin receptor. The pharmacological profile suggests the presence of a receptor which shares some properties with but appears different from other previously described serotonin receptors.

Entities: Chemical Species

Mesh：

Substances：

Year: 1994 PMID： 8139699 DOI： 10.1007/bf00178200

Source DB: PubMed Journal: Naunyn Schmiedebergs Arch Pharmacol ISSN： 0028-1298 Impact factor: 3.000

82 in total

1. Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype.

Authors: G McAllister; A Charlesworth; C Snodin; M S Beer; A J Noble; D N Middlemiss; L L Iversen; P Whiting
Journal: Proc Natl Acad Sci U S A Date: 1992-06-15 Impact factor: 11.205

2. Cloning and characterization of a Drosophila serotonin receptor that activates adenylate cyclase.

Authors: P Witz; N Amlaiky; J L Plassat; L Maroteaux; E Borrelli; R Hen
Journal: Proc Natl Acad Sci U S A Date: 1990-11 Impact factor: 11.205

3. BRL 24924: a potent agonist at a non-classical 5-HT receptor positively coupled with adenylate cyclase in colliculi neurons.

Authors: A Dumuis; M Sebben; J Bockaert
Journal: Eur J Pharmacol Date: 1989-03-21 Impact factor: 4.432

4. Olfaction by melanophores: what does it mean?

Authors: M R Lerner; J Reagan; T Gyorgyi; A Roby
Journal: Proc Natl Acad Sci U S A Date: 1988-01 Impact factor: 11.205

5. 5-Hydroxytryptamine 5-HT1B and 5-HT1D receptors mediating inhibition of adenylate cyclase activity. Pharmacological comparison with special reference to the effects of yohimbine, rauwolscine and some beta-adrenoceptor antagonists.

Authors: P Schoeffter; D Hoyer
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 1989-09 Impact factor: 3.000

6. Role of cyclic AMP in mediating the effects of MSH, norepinephrine, and melatonin on frog skin color.

Authors: K Abe; G A Robison; G W Liddle; R W Butcher; W E Nicholson; C E Baird
Journal: Endocrinology Date: 1969-10 Impact factor: 4.736

Review 7. A proposed new nomenclature for 5-HT receptors.

Authors: P P Humphrey; P Hartig; D Hoyer
Journal: Trends Pharmacol Sci Date: 1993-06 Impact factor: 14.819

8. A nonclassical 5-hydroxytryptamine receptor positively coupled with adenylate cyclase in the central nervous system.

Authors: A Dumuis; R Bouhelal; M Sebben; R Cory; J Bockaert
Journal: Mol Pharmacol Date: 1988-12 Impact factor: 4.436

9. The gastrointestinal prokinetic benzamide derivatives are agonists at the non-classical 5-HT receptor (5-HT4) positively coupled to adenylate cyclase in neurons.

Authors: A Dumuis; M Sebben; J Bockaert
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 1989-10 Impact factor: 3.000

10. Adenosine 3',5'-monophosphate (cyclic AMP) as the mediator of the actions of melanocyte stimulating hormone (MSH) and norepinephrine on the frog skin.

Authors: K Abe; R W Butcher; W E Nicholson; C E Baird; R A Liddle; G W Liddle
Journal: Endocrinology Date: 1969-02 Impact factor: 4.736

4 in total

1. 5-HT receptors as novel targets for optimizing pigmentary responses in dorsal skin melanophores of frog, Hoplobatrachus tigerinus.

Authors: Sharique A Ali; Saima Salim; Tarandeep Sahni; Jaya Peter; Ayesha S Ali
Journal: Br J Pharmacol Date: 2012-03 Impact factor: 8.739