Literature DB >> 8138227

Cocaine and metabolites in the hair of ancient Peruvian coca leaf chewers.

A C Springfield1, L W Cartmell, A C Aufderheide, J Buikstra, J Ho.   

Abstract

Cocaine and its metabolites, benzoylecgonine (BZE) and ecgonine methylester (EME), were found in hair samples from ancient Peruvian coca-leaf chewers dating back to AD 1000. Hair was analyzed by gas chromatography/mass spectrometry (GC/MS) to quantitate the concentrations. The two metabolites were found in higher concentration than the parent drug. The metabolite levels appear to be below that of modern cocaine abusers. Gender does not appear to be a factor in the incorporation of drug into hair.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8138227     DOI： 10.1016/0379-0738(93)90280-n

Source DB:  PubMed          Journal:  Forensic Sci Int        ISSN： 0379-0738            Impact factor:   2.395


  5 in total

1.  Stable isotope and DNA evidence for ritual sequences in Inca child sacrifice.

Authors:  Andrew S Wilson; Timothy Taylor; Maria Constanza Ceruti; Jose Antonio Chavez; Johan Reinhard; Vaughan Grimes; Wolfram Meier-Augenstein; Larry Cartmell; Ben Stern; Michael P Richards; Michael Worobey; Ian Barnes; M Thomas P Gilbert
Journal:  Proc Natl Acad Sci U S A       Date:  2007-10-08       Impact factor: 11.205

2.  Chemical evidence for the use of multiple psychotropic plants in a 1,000-year-old ritual bundle from South America.

Authors:  Melanie J Miller; Juan Albarracin-Jordan; Christine Moore; José M Capriles
Journal:  Proc Natl Acad Sci U S A       Date:  2019-05-06       Impact factor: 11.205

3.  Possibilities for discrimination between chewing of coca leaves and abuse of cocaine by hair analysis including hygrine, cuscohygrine, cinnamoylcocaine and cocaine metabolite/cocaine ratios.

Authors:  Nelida Cristina Rubio; Martin Hastedt; Jorge Gonzalez; Fritz Pragst
Journal:  Int J Legal Med       Date:  2014-08-20       Impact factor: 2.686

4.  Cannabinoid concentrations in hair from documented cannabis users.

Authors:  Marilyn A Huestis; Richard A Gustafson; Eric T Moolchan; Allan Barnes; James A Bourland; Stacy A Sweeney; Eugene F Hayes; Patrick M Carpenter; Michael L Smith
Journal:  Forensic Sci Int       Date:  2006-09-11       Impact factor: 2.395

5.  Homicidal poisoning series in a nursing home: retrospective toxicological investigations in bone marrow and hair.

Authors:  Théo Willeman; Nathalie Allibe; Laura Sauerbach; Anne Barret; Hélène Eysseric-Guerin; François Paysant; Françoise Stanke-Labesque; Virgine Scolan
Journal:  Int J Legal Med       Date:  2021-09-30       Impact factor: 2.686
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.