Literature DB >> 8138126

Isolation and biological characterization of staphyloferrin B, a compound with siderophore activity from staphylococci.

H Haag1, H P Fiedler, J Meiwes, H Drechsel, G Jung, H Zähner.   

Abstract

A highly hydrophilic compound with siderophore activity has been isolated from the supernatant of Staphylococcus hyicus DSM 20459 grown under iron-restricted conditions. The metabolite, named staphyloferrin B, is strictly iron-regulated and produced by a large variety of staphylococci strains. In vivo iron transport measurements and the growth-promoting activity in a bioassay establish staphyloferrin B as the second siderophore for staphylococci besides the previously described staphyloferrin A. The structure elucidation revealed 2,3-diaminopropionic acid, citrate, ethylenediamine and 2-ketoglutaric acid as structural components of the compound. Thus, staphyloferrin B is a structurally new siderophore of the complexone type.

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Year:  1994        PMID: 8138126     DOI: 10.1111/j.1574-6968.1994.tb06626.x

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN: 0378-1097            Impact factor:   2.742


  28 in total

1.  Hydroxylated phytosiderophore species possess an enhanced chelate stability and affinity for iron(III).

Authors:  N von Wirén; H Khodr; R C Hider
Journal:  Plant Physiol       Date:  2000-11       Impact factor: 8.340

2.  Structure and membrane affinity of new amphiphilic siderophores produced by Ochrobactrum sp. SP18.

Authors:  Jessica D Martin; Yusai Ito; Vanessa V Homann; Margo G Haygood; Alison Butler
Journal:  J Biol Inorg Chem       Date:  2006-05-20       Impact factor: 3.358

3.  Siderophore production by Staphylococcus aureus and identification of iron-regulated proteins.

Authors:  R J Courcol; D Trivier; M C Bissinger; G R Martin; M R Brown
Journal:  Infect Immun       Date:  1997-05       Impact factor: 3.441

4.  Baulamycins A and B, broad-spectrum antibiotics identified as inhibitors of siderophore biosynthesis in Staphylococcus aureus and Bacillus anthracis.

Authors:  Ashootosh Tripathi; Michael M Schofield; George E Chlipala; Pamela J Schultz; Isaiah Yim; Sean A Newmister; Tyler D Nusca; Jamie B Scaglione; Philip C Hanna; Giselle Tamayo-Castillo; David H Sherman
Journal:  J Am Chem Soc       Date:  2014-01-17       Impact factor: 15.419

5.  Identification and characterization of the two-enzyme system catalyzing oxidation of EDTA in the EDTA-degrading bacterial strain DSM 9103.

Authors:  M Witschel; S Nagel; T Egli
Journal:  J Bacteriol       Date:  1997-11       Impact factor: 3.490

6.  Role of siderophore biosynthesis in virulence of Staphylococcus aureus: identification and characterization of genes involved in production of a siderophore.

Authors:  Suzanne E Dale; Amanda Doherty-Kirby; Gilles Lajoie; David E Heinrichs
Journal:  Infect Immun       Date:  2004-01       Impact factor: 3.441

7.  Involvement of SirABC in iron-siderophore import in Staphylococcus aureus.

Authors:  Suzanne E Dale; M Tom Sebulsky; David E Heinrichs
Journal:  J Bacteriol       Date:  2004-12       Impact factor: 3.490

Review 8.  Beyond iron: non-classical biological functions of bacterial siderophores.

Authors:  Timothy C Johnstone; Elizabeth M Nolan
Journal:  Dalton Trans       Date:  2015-04-14       Impact factor: 4.390

9.  Purification and chemical characterization of staphyloferrin B, a hydrophilic siderophore from staphylococci.

Authors:  H Drechsel; S Freund; G Nicholson; H Haag; O Jung; H Zähner; G Jung
Journal:  Biometals       Date:  1993       Impact factor: 2.949

10.  Specificity of Staphyloferrin B recognition by the SirA receptor from Staphylococcus aureus.

Authors:  Jason C Grigg; Johnson Cheung; David E Heinrichs; Michael E P Murphy
Journal:  J Biol Chem       Date:  2010-09-01       Impact factor: 5.157

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