Literature DB >> 8135482

Low doses of interleukin-2 can cure large bovine ocular squamous cell carcinoma.

W Den Otter1, F W Hill, W R Klein, J W Koten, P A Steerenberg, P H De Mulder, V P Rutten, E J Ruitenberg.   

Abstract

Four cows bearing large Ocular Squamous Cell Carcinomas (BOSCC) were treated by 10 intratumoral injections (Monday-Friday for 2 consecutive weeks) of 200,000 U Interleukin-2 (Cetus). Tumors regressed in 2 out of 4 cases. This result shows that even large tumors may regress after local IL-2 treatment.

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Year:  1993        PMID： 8135482

Source DB:  PubMed          Journal:  Anticancer Res        ISSN： 0250-7005            Impact factor:   2.480


  3 in total

1.  Locoregional IL-2 low dose applications for gastrointestinal tumors.

Authors:  Zachary Krastev; V Koltchakov; R Tomova; S Deredjian; A Alexiev; D Popov; B Tomov; Jan-Willem Koten; John Jacobs; Willem Den Otter
Journal:  World J Gastroenterol       Date:  2005-09-21       Impact factor: 5.742

2.  Therapy of bovine ocular squamous-cell carcinoma with local doses of interleukin-2: 67% complete regressions after 20 months of follow-up.

Authors:  W Den Otter; F W Hill; W R Klein; J W Koten; P A Steerenberg; P H De Mulder; C Rhode; R Stewart; J A Faber; E J Ruitenberg
Journal:  Cancer Immunol Immunother       Date:  1995-07       Impact factor: 6.968

3.  Local therapy of cancer with free IL-2.

Authors:  Willem Den Otter; John J L Jacobs; Jan J Battermann; Gerrit Jan Hordijk; Zachary Krastev; Ekaterina V Moiseeva; Rachel J E Stewart; Paul G P M Ziekman; Jan Willem Koten
Journal:  Cancer Immunol Immunother       Date:  2008-07       Impact factor: 6.968
  3 in total

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