| Literature DB >> 8134417 |
A Favel1, M D Steinmetz, P Regli, E Vidal-Ollivier, R Elias, G Balansard.
Abstract
The antifungal activity of triterpenoid saponins, with hederagenin or oleanolic acid as aglycone, was investigated in vitro by the agar dilution method. Monodesmosidic hederagenin derivatives were shown to exhibit a broad spectrum of activity against yeast as well as dermatophyte species. alpha-Hederin was the most active compound, and Candida glabrata was the most susceptible strain. The structure-activity relationships are discussed.Entities:
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Year: 1994 PMID: 8134417 DOI: 10.1055/s-2006-959407
Source DB: PubMed Journal: Planta Med ISSN: 0032-0943 Impact factor: 3.352