Literature DB >> 8134123

SAS, a gene amplified in human sarcomas, encodes a new member of the transmembrane 4 superfamily of proteins.

S A Jankowski1, D S Mitchell, S H Smith, J M Trent, P S Meltzer.   

Abstract

Amplification of 12q13-14 occurs in a subset of human sarcomas including malignant fibrous histiocytoma and liposarcoma. This chromosomal region has previously been found to include a number of growth-related genes including the GLI proto-oncogene and the p53-associated protein, MDM2. We now report the characterization of SAS (sarcoma amplified sequence), a novel transcript found in this region. Sequence analysis demonstrates that SAS is a novel member of a transmembrane protein family (transmembrane 4 superfamily or TM4SF) thought to be involved in growth-related cellular processes. This observation adds a TM4SF protein to the cluster of genes at 12q13-14 frequently amplified in human sarcomas.

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Year:  1994        PMID： 8134123

Source DB:  PubMed          Journal:  Oncogene        ISSN： 0950-9232            Impact factor:   9.867


  16 in total

1.  The L6 membrane proteins--a new four-transmembrane superfamily.

Authors:  M D Wright; J Ni; G B Rudy
Journal:  Protein Sci       Date:  2000-08       Impact factor: 6.725

2.  Comparative genomic hybridization of malignant fibrous histiocytoma reveals a novel prognostic marker.

Authors:  M L Larramendy; M Tarkkanen; C Blomqvist; M Virolainen; T Wiklund; S Asko-Seljavaara; I Elomaa; S Knuutila
Journal:  Am J Pathol       Date:  1997-10       Impact factor: 4.307

Review 3.  Tetraspanins in viral infections: a fundamental role in viral biology?

Authors:  F Martin; D M Roth; D A Jans; C W Pouton; L J Partridge; P N Monk; G W Moseley
Journal:  J Virol       Date:  2005-09       Impact factor: 5.103

4.  Mapping of the genes for four members of the transmembrane 4 superfamily: mouse Cd9, Cd63, Cd81, and Cd82.

Authors:  M F Seldin; J M Rochelle; M G Tomlinson; M D Wright
Journal:  Immunogenetics       Date:  1995       Impact factor: 2.846

5.  Comparative genomic hybridization using oligonucleotide microarrays and total genomic DNA.

Authors:  Michael T Barrett; Alicia Scheffer; Amir Ben-Dor; Nick Sampas; Doron Lipson; Robert Kincaid; Peter Tsang; Bo Curry; Kristin Baird; Paul S Meltzer; Zohar Yakhini; Laurakay Bruhn; Stephen Laderman
Journal:  Proc Natl Acad Sci U S A       Date:  2004-12-10       Impact factor: 11.205

6.  The Impact of the CD9 Tetraspanin on Lentivirus Infectivity and Exosome Secretion.

Authors:  Kai O Böker; Nicolas Lemus-Diaz; Rafael Rinaldi Ferreira; Lara Schiller; Stefan Schneider; Jens Gruber
Journal:  Mol Ther       Date:  2017-11-16       Impact factor: 11.454

7.  Direct isolation of genes encoded within a homogeneously staining region by chromosome microdissection.

Authors:  Y A Su; J M Trent; X Y Guan; P S Meltzer
Journal:  Proc Natl Acad Sci U S A       Date:  1994-09-13       Impact factor: 11.205

8.  SFA-1, a novel cellular gene induced by human T-cell leukemia virus type 1, is a member of the transmembrane 4 superfamily.

Authors:  H Hasegawa; Y Utsunomiya; K Kishimoto; K Yanagisawa; S Fujita
Journal:  J Virol       Date:  1996-05       Impact factor: 5.103

Review 9.  Update on genomic and molecular landscapes of well-differentiated liposarcoma and dedifferentiated liposarcoma.

Authors:  Jun Lu; David Wood; Evan Ingley; Sulev Koks; Daniel Wong
Journal:  Mol Biol Rep       Date:  2021-04-24       Impact factor: 2.316

10.  Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia.

Authors:  Hyog Young Kwon; Jeevisha Bajaj; Takahiro Ito; Allen Blevins; Takaaki Konuma; Joi Weeks; Nikki K Lytle; Claire S Koechlein; David Rizzieri; Charles Chuah; Vivian G Oehler; Roman Sasik; Gary Hardiman; Tannishtha Reya
Journal:  Cell Stem Cell       Date:  2015-07-23       Impact factor: 24.633
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