Literature DB >> 8129855

Leucine synthesis in spinach chloroplasts: partial characterization of 2-isopropylmalate synthase.

P Hagelstein1, G Schultz.   

Abstract

Leucine synthesis was found to be localized in chloroplasts of higher plants. The introductory enzyme of the isopropylmalate pathway, the 2-isopropylmalate synthase, was strongly feedback-regulated by leucine. The pH optimum of the enzyme was between 7.0 and 9.0. The Km values were 5 microM for acetyl-CoA and 75 microM for 2-oxoisovalerate.

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Year:  1993        PMID： 8129855     DOI： 10.1515/bchm3.1993.374.7-12.1105

Source DB:  PubMed          Journal:  Biol Chem Hoppe Seyler        ISSN： 0177-3593


  14 in total

1.  Nucleus-encoded genes for plastid-targeted proteins in Helicosporidium: functional diversity of a cryptic plastid in a parasitic alga.

Authors:  Audrey P de Koning; Patrick J Keeling
Journal:  Eukaryot Cell       Date:  2004-10

2.  Branched-Chain Amino Acid Metabolism in Arabidopsis thaliana.

Authors:  Stefan Binder
Journal:  Arabidopsis Book       Date:  2010-08-23

3.  Different elongation pathways in the biosynthesis of acyl groups of trichome exudate sugar esters from various solanaceous plants.

Authors:  Antoaneta B Kroumova; George J Wagner
Journal:  Planta       Date:  2003-01-18       Impact factor: 4.116

4.  From amino acid to glucosinolate biosynthesis: protein sequence changes in the evolution of methylthioalkylmalate synthase in Arabidopsis.

Authors:  Jan-Willem de Kraker; Jonathan Gershenzon
Journal:  Plant Cell       Date:  2011-01-04       Impact factor: 11.277

5.  Expression of a Brassica isopropylmalate synthase gene in Arabidopsis perturbs both glucosinolate and amino acid metabolism.

Authors:  Ben Field; Caroline Furniss; Andrew Wilkinson; Richard Mithen
Journal:  Plant Mol Biol       Date:  2006-03       Impact factor: 4.076

Review 6.  Leucine biosynthesis in fungi: entering metabolism through the back door.

Authors:  Gunter B Kohlhaw
Journal:  Microbiol Mol Biol Rev       Date:  2003-03       Impact factor: 11.056

7.  Two Arabidopsis genes (IPMS1 and IPMS2) encode isopropylmalate synthase, the branchpoint step in the biosynthesis of leucine.

Authors:  Jan-Willem de Kraker; Katrin Luck; Susanne Textor; James G Tokuhisa; Jonathan Gershenzon
Journal:  Plant Physiol       Date:  2006-12-22       Impact factor: 8.340

8.  Arabidopsis branched-chain aminotransferase 3 functions in both amino acid and glucosinolate biosynthesis.

Authors:  Tanja Knill; Joachim Schuster; Michael Reichelt; Jonathan Gershenzon; Stefan Binder
Journal:  Plant Physiol       Date:  2007-12-27       Impact factor: 8.340

9.  MAM3 catalyzes the formation of all aliphatic glucosinolate chain lengths in Arabidopsis.

Authors:  Susanne Textor; Jan-Willem de Kraker; Bettina Hause; Jonathan Gershenzon; James G Tokuhisa
Journal:  Plant Physiol       Date:  2007-03-16       Impact factor: 8.340

10.  Biosynthesis of methionine-derived glucosinolates in Arabidopsis thaliana: recombinant expression and characterization of methylthioalkylmalate synthase, the condensing enzyme of the chain-elongation cycle.

Authors:  Susanne Textor; Stefan Bartram; Jürgen Kroymann; Kimberly L Falk; Alastair Hick; John A Pickett; Jonathan Gershenzon
Journal:  Planta       Date:  2004-01-22       Impact factor: 4.116
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