Literature DB >> 8127925

Paracetamol (acetaminophen) poisoning.

S H Thomas1.   

Abstract

Paracetamol poisoning caused by intentional overdose remains a common cause of morbidity. In this article the mechanism of toxicity and the clinical effects and treatment of poisoning, including specific antidotal therapy, are reviewed. Areas for further research directed at reducing morbidity and mortality from paracetamol poisoning are considered.

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Year:  1993        PMID： 8127925     DOI： 10.1016/0163-7258(93)90023-7

Source DB:  PubMed          Journal:  Pharmacol Ther        ISSN： 0163-7258            Impact factor:   12.310


  26 in total

1.  N-acetyl-cysteine protects against DNA damage associated with lead toxicity in HepG2 cells.

Authors:  Clement G Yedjou; Christine K Tchounwou; Samuel Haile; Falicia Edwards; Paul B Tchounwou
Journal:  Ethn Dis       Date:  2010       Impact factor: 1.847

2.  TRPM2 channels mediate acetaminophen-induced liver damage.

Authors:  Ehsan Kheradpezhouh; Linlin Ma; Arthur Morphett; Greg J Barritt; Grigori Y Rychkov
Journal:  Proc Natl Acad Sci U S A       Date:  2014-02-03       Impact factor: 11.205

3.  Mechanistic study of TRPM2-Ca(2+)-CAMK2-BECN1 signaling in oxidative stress-induced autophagy inhibition.

Authors:  Qian Wang; Wenjing Guo; Baixia Hao; Xianli Shi; Yingying Lu; Connie W M Wong; Victor W S Ma; Timothy T C Yip; Joseph S K Au; Quan Hao; King-Ho Cheung; Wutian Wu; Gui-Rong Li; Jianbo Yue
Journal:  Autophagy       Date:  2016-05-31       Impact factor: 16.016

4.  Ubiquitin-dependent degradation of p53 protein despite phosphorylation at its N terminus by acetaminophen.

Authors:  Yun-Sik Lee; Jie Wan; Bong-Jo Kim; Myung-Ae Bae; Byoung J Song
Journal:  J Pharmacol Exp Ther       Date:  2005-12-05       Impact factor: 4.030

5.  Glutathione deficiency is associated with impaired survival in HIV disease.

Authors:  L A Herzenberg; S C De Rosa; J G Dubs; M Roederer; M T Anderson; S W Ela; S C Deresinski; L A Herzenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-04       Impact factor: 11.205

6.  Role of cytochrome P450 2E1 in protein nitration and ubiquitin-mediated degradation during acetaminophen toxicity.

Authors:  Mohamed A Abdelmegeed; Kwan-Hoon Moon; Chi Chen; Frank J Gonzalez; Byoung-Joon Song
Journal:  Biochem Pharmacol       Date:  2009-08-04       Impact factor: 5.858

7.  Moringa oleifera hydroethanolic extracts effectively alleviate acetaminophen-induced hepatotoxicity in experimental rats through their antioxidant nature.

Authors:  Sharida Fakurazi; Syazana Akmal Sharifudin; Palanisamy Arulselvan
Journal:  Molecules       Date:  2012-07-10       Impact factor: 4.411

8.  Protective effects of ginkgo biloba against acetaminophen-induced toxicity in mice.

Authors:  Göksel Sener; Gülden Z Omurtag; Ozer Sehirli; Ayfer Tozan; Meral Yüksel; Feriha Ercan; Nursal Gedik
Journal:  Mol Cell Biochem       Date:  2006-02       Impact factor: 3.396

Review 9.  Drug-induced liver injury in older adults.

Authors:  Sarah J Mitchell; Sarah N Hilmer
Journal:  Ther Adv Drug Saf       Date:  2010-12

10.  Relationship of Oxidative Stress with HIV Disease Progression in HIV/HCV Co-infected and HIV Mono-infected Adults in Miami.

Authors:  Dong-Ho Shin; Sabrina S Martinez; Mary Parsons; Dushyantha T Jayaweera; Adriana Campa; Marianna K Baum
Journal:  Int J Biosci Biochem Bioinforma       Date:  2012
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