Literature DB >> 8127711

DNA ligase I is associated with the 21 S complex of enzymes for DNA synthesis in HeLa cells.

C Li1, J Goodchild, E F Baril.   

Abstract

Approximately 80% of the DNA ligase activity in HeLa cell extracts is associated with the 21 S enzyme complex that functions in simian virus 40 DNA replication in vitro (Malkas et al., Biochemistry 29, 6362-6374., 1990). The DNA ligase associated with the 21 S complex was purified extensively and its physical, enzymic and immunological properties characterized as DNA ligase I. The association of DNA ligase I with the 21 S complex of enzymes for DNA synthesis provides evidence for the physiological function of this DNA ligase in DNA replication in human cells.

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Year:  1994        PMID： 8127711      PMCID： PMC307854          DOI： 10.1093/nar/22.4.632

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  33 in total

1.  A novel assay for DNA ligase.

Authors:  J Goodchild; J K Vishwanatha
Journal:  Nucleic Acids Res       Date:  1991-07-11       Impact factor: 16.971

2.  Nuclear DNA polymerases and the HeLa cell cycle.

Authors:  R W Chiu; E F Baril
Journal:  J Biol Chem       Date:  1975-10-10       Impact factor: 5.157

3.  Single-stranded-DNA-dependent ATPase from HeLa cells that stimulates DNA polymerase alpha-primase activity: purification and characterization of the ATPase.

Authors:  J K Vishwanatha; E F Baril
Journal:  Biochemistry       Date:  1990-09-18       Impact factor: 3.162

4.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

Authors:  M M Bradford
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

5.  Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Authors:  H Towbin; T Staehelin; J Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

6.  Enzymatic breadage and joining of deoxyribonucleic acid. 3. An enzyme-adenylate intermediate in the polynucleotide ligase reaction.

Authors:  B Weiss; C C Richardson
Journal:  J Biol Chem       Date:  1967-09-25       Impact factor: 5.157

7.  Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases.

Authors:  L M Siegel; K J Monty
Journal:  Biochim Biophys Acta       Date:  1966-02-07

8.  Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei.

Authors:  L F Liu; K G Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1981-06       Impact factor: 11.205

9.  Mammalian DNA ligases. Serological evidence for two separate enzymes.

Authors:  S Söderhäll; T Lindahl
Journal:  J Biol Chem       Date:  1975-11-10       Impact factor: 5.157

10.  Rat liver DNA ligases. Catalytic properties of a novel form of DNA ligase.

Authors:  R H Elder; A Montecucco; G Ciarrocchi; J M Rossignol
Journal:  Eur J Biochem       Date:  1992-01-15
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  6 in total

1.  Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair.

Authors:  S H Teo; S P Jackson
Journal:  EMBO J       Date:  1997-08-01       Impact factor: 11.598

2.  An interaction between DNA ligase I and proliferating cell nuclear antigen: implications for Okazaki fragment synthesis and joining.

Authors:  D S Levin; W Bai; N Yao; M O'Donnell; A E Tomkinson
Journal:  Proc Natl Acad Sci U S A       Date:  1997-11-25       Impact factor: 11.205

3.  Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination.

Authors:  Y F Wei; P Robins; K Carter; K Caldecott; D J Pappin; G L Yu; R P Wang; B K Shell; R A Nash; P Schär
Journal:  Mol Cell Biol       Date:  1995-06       Impact factor: 4.272

4.  Two distinct DNA ligase activities in mitotic extracts of the yeast Saccharomyces cerevisiae.

Authors:  W Ramos; N Tappe; J Talamantez; E C Friedberg; A E Tomkinson
Journal:  Nucleic Acids Res       Date:  1997-04-15       Impact factor: 16.971

5.  Mapping and use of a sequence that targets DNA ligase I to sites of DNA replication in vivo.

Authors:  M C Cardoso; C Joseph; H P Rahn; R Reusch; B Nadal-Ginard; H Leonhardt
Journal:  J Cell Biol       Date:  1997-11-03       Impact factor: 10.539

6.  The N-terminal domain of human DNA ligase I contains the nuclear localization signal and directs the enzyme to sites of DNA replication.

Authors:  A Montecucco; E Savini; F Weighardt; R Rossi; G Ciarrocchi; A Villa; G Biamonti
Journal:  EMBO J       Date:  1995-11-01       Impact factor: 11.598
  6 in total

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