Literature DB >> 8127582

Wegener's granulomatosis. Eyelid and conjunctival manifestations as the presenting feature in two individuals.

D R Jordan1, D J Addison.   

Abstract

BACKGROUND: Wegener's granulomatosis is a necrotizing granulomatous vasculitis that may exist in a generalized or limited form and has a variety of unusual and uncommon presentations. Although ocular manifestations are relatively common in the disease at some point, the eyelid and its conjunctival lining are rarely involved. When this area is the initial focus of the disease, diagnosis may be difficult.
RESULTS: The authors present two patients with Wegener's granulomatosis who had involvement of the palpebral conjunctiva as the initial manifestation.
CONCLUSION: Eyelid and conjunctival involvement in Wegener's granulomatosis is uncommon. When it is the initial manifestation of this disease, a diagnosis of Wegener's may be delayed unless this unusual presentation is recognized.

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Year:  1994        PMID: 8127582     DOI: 10.1016/s0161-6420(94)31295-4

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  7 in total

1.  Orbital socket contracture: a complication of inflammatory orbital disease in patients with Wegener's granulomatosis.

Authors:  C Talar-Williams; M C Sneller; C A Langford; J A Smith; T A Cox; M R Robinson
Journal:  Br J Ophthalmol       Date:  2005-04       Impact factor: 4.638

2.  Atypical Conjunctival Lesion as the Initial Presentation of Granulomatosis With Polyangiitis in an Adolescent Male.

Authors:  Wathanee Sripawadkul; Mike Zein; Anat Galor; Rafael Rivas-Chacon; Rayan Abou Khzam; Sander R Dubovy; Carol L Karp
Journal:  Cornea       Date:  2022-03-30       Impact factor: 3.152

3.  Florid xanthelasmata (yellow lids) in orbital Wegener's granulomatosis.

Authors:  A B Tullo; P Durrington; E Graham; L P Holt; D L Easty; R Bonshek; J L Noble
Journal:  Br J Ophthalmol       Date:  1995-05       Impact factor: 4.638

Review 4.  [Classification of ocular surface disease. Part 1].

Authors:  F E Kruse; C Cursiefen; B Seitz; H E Völcker; G O H Naumann; L Holbach
Journal:  Ophthalmologe       Date:  2003-11       Impact factor: 1.174

5.  The role of conjunctival biopsy in the diagnosis of granulomatosis with polyangiitis.

Authors:  Roxana Ursea; Dawn De Castro; Trent J Bowen; Chi-Chao Chan
Journal:  J Ophthalmic Inflamm Infect       Date:  2015-01-23

6.  A case of Granulomatosis with Polyangiitis presenting with significant ocular cicatricial scarring and symblepharon formation.

Authors:  Kevin Dunne; Muhammad Khalid
Journal:  Am J Ophthalmol Case Rep       Date:  2016-07-01

7.  Conjunctivitis as a manifestation of Wegener's Granulomatosis.

Authors:  Mahmoud Nejabat; Golnoush Sadat Mahmoudi Nezhad; Saeedeh Shenavandeh; Mohammad Javad Ashraf; Mohammad Hassan Jalalpour
Journal:  J Curr Ophthalmol       Date:  2017-12-13
  7 in total

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