PURPOSE: To investigate variations in diabetic short-wavelength sensitivity with acute, induced changes in blood glucose level. METHODS: Increment threshold measures were obtained for short-wavelength-sensitive and middle/long-wavelength-sensitive cone pathways after an induced, acute change in blood glucose level in diabetic observers. RESULTS: Diabetic observers showed an increase in short-wavelength sensitivity, but no change in middle/long-wavelength sensitivity, with a rapid drop in blood glucose level. CONCLUSIONS: Experimentally induced changes in diabetic blood glucose levels can directly affect diabetic short-wavelength sensitivity.
PURPOSE: To investigate variations in diabetic short-wavelength sensitivity with acute, induced changes in blood glucose level. METHODS: Increment threshold measures were obtained for short-wavelength-sensitive and middle/long-wavelength-sensitive cone pathways after an induced, acute change in blood glucose level in diabetic observers. RESULTS:Diabetic observers showed an increase in short-wavelength sensitivity, but no change in middle/long-wavelength sensitivity, with a rapid drop in blood glucose level. CONCLUSIONS: Experimentally induced changes in diabetic blood glucose levels can directly affect diabetic short-wavelength sensitivity.
Authors: Marcus A Bearse; Anthony J Adams; Ying Han; Marilyn E Schneck; Jason Ng; Kevin Bronson-Castain; Shirin Barez Journal: Prog Retin Eye Res Date: 2006-09-01 Impact factor: 21.198