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Literature DB >> 8125171

Relevance of chlorine-substituent for the antifungal activity of syringomycin and syringotoxin, metabolites of the phytopathogenic bacterium Pseudomonas syringae pv. syringae.

I Grgurina¹, A Barca, S Cervigni, M Gallo, A Scaloni, P Pucci.

Abstract

Structural analogues of syringomycin and syringotoxin were produced by fermentation, characterized by FAB-MS and amino acid analysis and compared to the parent compounds in the antibiosis test against Rhodotorula pilimanae. The C-terminal residue was shown to be important for the activity.

Entities: Chemical Species

Mesh：

Substances：

Year: 1994 PMID： 8125171 DOI： 10.1007/bf01984950

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

6 in total

1. Effect of halogens on the chloramphenicol fermentation.

Authors: C G SMITH
Journal: J Bacteriol Date: 1958-05 Impact factor: 3.490

2. Evaluation of the Role of Syringomycin in Plant Pathogenesis by Using Tn5 Mutants of Pseudomonas syringae pv. syringae Defective in Syringomycin Production.

Authors: G W Xu; D C Gross
Journal: Appl Environ Microbiol Date: 1988-06 Impact factor: 4.792

3. A new antifungal substance, bromomonilicin, and its precursor produced by Monilinia fructicola.

Authors: H Kachi; H Hattori; T Sassa
Journal: J Antibiot (Tokyo) Date: 1986-01 Impact factor: 2.649

4. Structure of syringotoxin, a bioactive metabolite of Pseudomonas syringae pv. syringae.

Authors: A Ballio; F Bossa; A Collina; M Gallo; N S Iacobellis; M Paci; P Pucci; A Scaloni; A Segre; M Simmaco
Journal: FEBS Lett Date: 1990-09-03 Impact factor: 4.124

5. The structure of syringomycins A1, E and G.

Authors: A Segre; R C Bachmann; A Ballio; F Bossa; I Grgurina; N S Iacobellis; G Marino; P Pucci; M Simmaco; J Y Takemoto
Journal: FEBS Lett Date: 1989-09-11 Impact factor: 4.124

6. Syringopeptins, new phytotoxic lipodepsipeptides of Pseudomonas syringae pv. syringae.

Authors: A Ballio; D Barra; F Bossa; A Collina; I Grgurina; G Marino; G Moneti; M Paci; P Pucci; A Segre
Journal: FEBS Lett Date: 1991-10-07 Impact factor: 4.124

6 in total

9 in total

1. Substrate placement influences reactivity in non-heme Fe(II) halogenases and hydroxylases.

Authors: Heather J Kulik; Catherine L Drennan
Journal: J Biol Chem Date: 2013-02-28 Impact factor: 5.157

Review 2. Pseudomonas syringae phytotoxins: mode of action, regulation, and biosynthesis by peptide and polyketide synthetases.

Authors: C L Bender; F Alarcón-Chaidez; D C Gross
Journal: Microbiol Mol Biol Rev Date: 1999-06 Impact factor: 11.056

Review 3. Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse.

Authors: Vinayak Agarwal; Zachary D Miles; Jaclyn M Winter; Alessandra S Eustáquio; Abrahim A El Gamal; Bradley S Moore
Journal: Chem Rev Date: 2017-01-20 Impact factor: 60.622

4. Theoretical investigation on the oxidative chlorination performed by a biomimetic non-heme iron catalyst.

Authors: Holger Noack; Per E M Siegbahn
Journal: J Biol Inorg Chem Date: 2007-08-14 Impact factor: 3.358

5. Regioselectivity of substrate hydroxylation versus halogenation by a nonheme iron(IV)-oxo complex: possibility of rearrangement pathways.

Authors: Matthew G Quesne; Sam P de Visser
Journal: J Biol Inorg Chem Date: 2012-05-13 Impact factor: 3.358