| Literature DB >> 8124768 |
K Kondo1, M Takahashi, H Ohmizu, M Matsumoto, I Taguchi, T Iwasaki.
Abstract
2,2'-Disubstituted biphenyl compounds (1-15) were synthesized by using the Ullmann coupling reaction as a key step. The suppressive effect of these compounds against CCl4-induced liver injuries in mice was evaluated. An unsymmetrical biphenyl (14f) exhibited the most potent activity. The structure-activity relationship is discussed.Entities:
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Year: 1994 PMID： 8124768 DOI： 10.1248/cpb.42.62
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645