Literature DB >> 8123050

Identification of natural killer enhancing factor as a major antioxidant in human red blood cells.

H Shau1, A Kim.   

Abstract

Human natural killer enhancing factor genes (NKEF-A and B) share extensive homology with several genes from other organisms known to be induced by oxidative stress and to protect organisms and proteins from oxidative destruction. In this study, we have identified natural killer enhancing factor as an abundant protein in red blood cell cytosol. Highly purified natural killer enhancing factor blocks inactivation of enzymes by mixed metal-thiol oxidation. Thus, natural killer enhancing factor is a major antioxidant protecting red blood cells from oxidative injuries.

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Year:  1994        PMID： 8123050     DOI： 10.1006/bbrc.1994.1197

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  11 in total

1.  Genomic organization, single nucleotide polymorphism and functional characterization of natural killer enhancing factor (NKEF-A) in Miichthys miiuy.

Authors:  Fanqiang Meng; Rixin Wang; Yunhang Gao; Tianjun Xu
Journal:  Mol Biol Rep       Date:  2013-12-19       Impact factor: 2.316

2.  Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury.

Authors:  F Amersi; R Buelow; H Kato; B Ke; A J Coito; X D Shen; D Zhao; J Zaky; J Melinek; C R Lassman; J K Kolls; J Alam; T Ritter; H D Volk; D G Farmer; R M Ghobrial; R W Busuttil; J W Kupiec-Weglinski
Journal:  J Clin Invest       Date:  1999-12       Impact factor: 14.808

Review 3.  Thioredoxin and thioredoxin target proteins: from molecular mechanisms to functional significance.

Authors:  Samuel Lee; Soo Min Kim; Richard T Lee
Journal:  Antioxid Redox Signal       Date:  2012-06-26       Impact factor: 8.401

4.  Cloning and sequencing of thiol-specific antioxidant from mammalian brain: alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes.

Authors:  H Z Chae; K Robison; L B Poole; G Church; G Storz; S G Rhee
Journal:  Proc Natl Acad Sci U S A       Date:  1994-07-19       Impact factor: 11.205

5.  Cysteine Oxidation Targets Peroxiredoxins 1 and 2 for Exosomal Release through a Novel Mechanism of Redox-Dependent Secretion.

Authors:  Lisa Mullen; Eva-Maria Hanschmann; Christopher Horst Lillig; Leonore A Herzenberg; Pietro Ghezzi
Journal:  Mol Med       Date:  2015-02-13       Impact factor: 6.354

6.  Peroxiredoxin 2 is upregulated in colorectal cancer and contributes to colorectal cancer cells' survival by protecting cells from oxidative stress.

Authors:  Weidong Lu; Zhongxue Fu; Hao Wang; Jihong Feng; Jinlai Wei; Jinbao Guo
Journal:  Mol Cell Biochem       Date:  2013-11-15       Impact factor: 3.396

7.  Expression of the p75 TNF receptor is linked to TNF-induced NFkappaB translocation and oxyradical neutralization in glial cells.

Authors:  Joel M Dopp; Theodore A Sarafian; Francesca M Spinella; Michelle A Kahn; Hungyi Shau; Jean de Vellis
Journal:  Neurochem Res       Date:  2002-11       Impact factor: 3.996

8.  Early events in erythroid differentiation: accumulation of the acidic peroxidoxin (PRP/TSA/NKEF-B).

Authors:  T Rabilloud; R Berthier; M Vinçon; D Ferbus; G Goubin; J J Lawrence
Journal:  Biochem J       Date:  1995-12-15       Impact factor: 3.857

9.  Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis.

Authors:  Hsiang-Hao Hsu; Sigrid Hoffmann; Giovana S Di Marco; Nicole Endlich; Jasna Peter-Katalinić; Thomas Weide; Hermann Pavenstädt
Journal:  Kidney Int       Date:  2011-08-03       Impact factor: 10.612

Review 10.  The role of peroxiredoxin II in chemoresistance of breast cancer cells.

Authors:  Tieli Wang; Anthony Joseph Gomez Diaz; Yun Yen
Journal:  Breast Cancer (Dove Med Press)       Date:  2014-05-23
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