Literature DB >> 8121729

Management of children with slightly elevated blood lead levels.

R D Kimbrough1, M LeVois, D R Webb.   

Abstract

OBJECTIVE: To determine whether counseling of parents reduced blood lead levels in their young children. PARTICIPANTS AND METHODS: A lead exposure study was conducted in the vicinity of a defunct lead smelter. A total of 827 volunteers including 490 children younger than 6 years participated in the study. The mean venous blood lead level in the 490 children was 0.33 mumol/L (6.9 micrograms/dL), with a range of 0.03 to 1.94 mumol/L (0.7 to 40.2 micrograms/dL). A total of 78 (16%) children had blood lead levels > or = 0.48 mumol/L (10 micrograms/dL). However, only 5 (1%) of the children had blood lead levels of > or = 1.21 mumol/L (25 micrograms/dL). The blood lead levels in this community were much lower than levels reported in earlier studies in many areas of the United States, when lead levels in air and in food were higher. Most houses in the study community were built before 1920 and had high lead paint levels. High levels of lead were also found in many house dust and soil samples. Intervention consisted of home visits and counseling of parents of children with blood lead levels of > or = 0.48 mumol/L (10 micrograms/dL).
RESULTS: In children with initial blood lead levels of > or = 0.48 mumol/L (10 micrograms/dL) the blood lead test was repeated 4 months later. The arithmetic mean blood lead level 4 months later showed a decrease from 0.72 mumol/L (15 micrograms/dL) to 0.38 mumol/L (7.8 micrograms/dL). An additional blood sample was taken 1 year after the first sample in a subset of 30 children. These children showed a mean blood lead level of 0.43 mumol/L (9 micrograms/dL) at the 1-year follow-up, whereas their mean blood lead level at the 4-month follow-up had been 0.38 mumol/L (8 micrograms/dL).
CONCLUSION: Educating parents proved a very effective tool. Further studies are needed in larger populations to evaluate the effectiveness of this approach.

Entities:  

Mesh:

Substances:

Year:  1994        PMID: 8121729

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  12 in total

1.  Seasonal variation in paediatric blood lead levels in Syracuse, NY, USA.

Authors:  D L Johnson; K McDade; D Griffith
Journal:  Environ Geochem Health       Date:  1996-06       Impact factor: 4.609

2.  A co-operative approach to risk management in an active lead/zinc smelter community.

Authors:  S R Hilts
Journal:  Environ Geochem Health       Date:  1996-03       Impact factor: 4.609

3.  Critique of CDC's retreat from recommending universal lead screening for children.

Authors:  E W Manheimer; E K Silbergeld
Journal:  Public Health Rep       Date:  1998 Jan-Feb       Impact factor: 2.792

4.  CDC's lead screening guidance: a systematic approach to more effective screening.

Authors:  N M Tips; H Falk; R J Jackson
Journal:  Public Health Rep       Date:  1998 Jan-Feb       Impact factor: 2.792

5.  Lead and cadmium levels in daily foods, blood and urine in children and their mothers in Korea.

Authors:  Chan-Seok Moon; Jong-Min Paik; Chang-Soo Choi; Do-Hoon Kim; Masayuki Ikeda
Journal:  Int Arch Occup Environ Health       Date:  2003-04-10       Impact factor: 3.015

Review 6.  Lead toxicity intervention in children.

Authors:  E H Norman; W C Bordley
Journal:  J R Soc Med       Date:  1995-03       Impact factor: 5.344

7.  Junior doctors' hours.

Authors:  T A Carney
Journal:  J R Soc Med       Date:  1995-02       Impact factor: 5.344

8.  Results from a lay health advisor intervention to prevent lead poisoning among rural Native American children.

Authors:  Michelle Crozier Kegler; Lorraine Halinka Malcoe
Journal:  Am J Public Health       Date:  2004-10       Impact factor: 9.308

9.  A noninvasive isotopic approach to estimate the bone lead contribution to blood in children: implications for assessing the efficacy of lead abatement.

Authors:  Roberto Gwiazda; Carla Campbell; Donald Smith
Journal:  Environ Health Perspect       Date:  2005-01       Impact factor: 9.031

10.  Cadmium-related mortality and long-term secular trends in the cadmium body burden of an environmentally exposed population.

Authors:  Tim S Nawrot; Etienne Van Hecke; Lutgarde Thijs; Tom Richart; Tatiana Kuznetsova; Yu Jin; Jaco Vangronsveld; Harry A Roels; Jan A Staessen
Journal:  Environ Health Perspect       Date:  2008-07-24       Impact factor: 9.031

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.