Literature DB >> 8121275

Magnetization transfer affects the proton creatine/phosphocreatine signal intensity: in vivo demonstration in the rat brain.

W Dreher1, D G Norris, D Leibfritz.   

Abstract

The effect of off-resonance preirradiation on proton spectra acquired from the healthy rat brain at 4.7 T is examined using a PRESS sequence. The creatine/phosphocreatine (Cr/PCr) signal at 3.0 ppm decreases in signal intensity for offset frequencies between +/- 10 kHz. This cannot be explained by RF bleedover, but is attributed to magnetization transfer between two pools of Cr/PCr, one with a long T2 relaxation time giving the observed NMR signal, the other corresponding to a broad resonance line being completely or partially saturated by off-resonance preirradiation. Possible interpretations of these results are discussed.

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Year:  1994        PMID： 8121275     DOI： 10.1002/mrm.1910310114

Source DB:  PubMed          Journal:  Magn Reson Med        ISSN： 0740-3194            Impact factor:   4.668


  8 in total

1.  Ethanol in human brain by magnetic resonance spectroscopy: correlation with blood and breath levels, relaxation, and magnetization transfer.

Authors:  G Fein; D J Meyerhoff
Journal:  Alcohol Clin Exp Res       Date:  2000-08       Impact factor: 3.455

Review 2.  A guide to the metabolic pathways and function of metabolites observed in human brain 1H magnetic resonance spectra.

Authors:  Caroline D Rae
Journal:  Neurochem Res       Date:  2013-11-21       Impact factor: 3.996

3.  T2 measurement of J-coupled metabolites in the human brain at 3T.

Authors:  Sandeep K Ganji; Abhishek Banerjee; Aditya M Patel; Yan D Zhao; Ivan E Dimitrov; Jeffrey D Browning; E Sherwood Brown; Elizabeth A Maher; Changho Choi
Journal:  NMR Biomed       Date:  2011-08-15       Impact factor: 4.044

4.  In vivo (1)H MRSI of glycine in brain tumors at 3T.

Authors:  Sandeep K Ganji; Elizabeth A Maher; Changho Choi
Journal:  Magn Reson Med       Date:  2015-02-04       Impact factor: 4.668

5.  Water and lipid suppression techniques for advanced 1 H MRS and MRSI of the human brain: Experts' consensus recommendations.

Authors:  Ivan Tkáč; Dinesh Deelchand; Wolfgang Dreher; Hoby Hetherington; Roland Kreis; Chathura Kumaragamage; Michal Považan; Daniel M Spielman; Bernhard Strasser; Robin A de Graaf
Journal:  NMR Biomed       Date:  2020-12-16       Impact factor: 4.478

6.  Application of ICA to realistically simulated (1)H-MRS data.

Authors:  Ravi Kalyanam; David Boutte; Kent E Hutchison; Vince D Calhoun
Journal:  Brain Behav       Date:  2015-04-25       Impact factor: 2.708

7.  Terminology and concepts for the characterization of in vivo MR spectroscopy methods and MR spectra: Background and experts' consensus recommendations.

Authors:  Roland Kreis; Vincent Boer; In-Young Choi; Cristina Cudalbu; Robin A de Graaf; Charles Gasparovic; Arend Heerschap; Martin Krššák; Bernard Lanz; Andrew A Maudsley; Martin Meyerspeer; Jamie Near; Gülin Öz; Stefan Posse; Johannes Slotboom; Melissa Terpstra; Ivan Tkáč; Martin Wilson; Wolfgang Bogner
Journal:  NMR Biomed       Date:  2020-08-17       Impact factor: 4.044

8.  Combining chemical exchange saturation transfer and 1 H magnetic resonance spectroscopy for simultaneous determination of metabolite concentrations and effects of magnetization exchange.

Authors:  Maike Hoefemann; André Döring; Nicole Damara Fichtner; Roland Kreis
Journal:  Magn Reson Med       Date:  2020-11-05       Impact factor: 4.668
  8 in total

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