Literature DB >> 8120457

Transforming growth factor beta: a matter of life and death.

N L McCartney-Francis1, S M Wahl.   

Abstract

A wide variety of functions, many of which represent opposing activities, have been attributed to TGF-beta, a molecule implicated in embryogenesis, development, and immune and inflammatory processes. This paradoxical behavior of promoting or inhibiting cell growth and function, while important in normal physiology and homeostasis, can contribute to or interrupt pathologic sequelae, making TGF-beta a particularly intriguing molecule for study. New transgenic mouse models displaying targeted alterations in TGF-beta 1 expression offer novel and unique opportunities to determine the essential function(s) of TGF-beta.

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Year:  1994        PMID： 8120457     DOI： 10.1002/jlb.55.3.401

Source DB:  PubMed          Journal:  J Leukoc Biol        ISSN： 0741-5400            Impact factor:   4.962


  59 in total

1.  Elevated expression of transforming growth factor-beta in adipose tissue from obese mice.

Authors:  F Samad; K Yamamoto; M Pandey; D J Loskutoff
Journal:  Mol Med       Date:  1997-01       Impact factor: 6.354

Review 2.  Novel mechanisms of class II major histocompatibility complex gene regulation.

Authors:  Michael Radosevich; Santa Jeremy Ono
Journal:  Immunol Res       Date:  2003       Impact factor: 2.829

3.  TGF-beta induces p65 acetylation to enhance bacteria-induced NF-kappaB activation.

Authors:  Hajime Ishinaga; Hirofumi Jono; Jae Hyang Lim; Soo-Mi Kweon; Haodong Xu; Un-Hwan Ha; Haidong Xu; Tomoaki Koga; Chen Yan; Xin-Hua Feng; Lin-Feng Chen; Jian-Dong Li
Journal:  EMBO J       Date:  2007-02-01       Impact factor: 11.598

4.  Autoimmunity associated with TGF-beta1-deficiency in mice is dependent on MHC class II antigen expression.

Authors:  J J Letterio; A G Geiser; A B Kulkarni; H Dang; L Kong; T Nakabayashi; C L Mackall; R E Gress; A B Roberts
Journal:  J Clin Invest       Date:  1996-11-01       Impact factor: 14.808

5.  Epidermal Smad4 deletion results in aberrant wound healing.

Authors:  Philip Owens; Erin Engelking; Gangwen Han; Sarah M Haeger; Xiao-Jing Wang
Journal:  Am J Pathol       Date:  2009-12-03       Impact factor: 4.307

6.  Transforming growth factor-beta and multidrug resistance in chronic lymphocytic leukemia.

Authors:  W R Friedenberg; S A Salzman; S M Phan; J K Burmester
Journal:  Med Oncol       Date:  1999-07       Impact factor: 3.064

Review 7.  Cytokine therapy in rheumatoid arthritis.

Authors:  J Hermann; M Walmsley; F M Brennan
Journal:  Springer Semin Immunopathol       Date:  1998

Review 8.  A primer on cytokines: sources, receptors, effects, and inducers.

Authors:  J H Curfs; J F Meis; J A Hoogkamp-Korstanje
Journal:  Clin Microbiol Rev       Date:  1997-10       Impact factor: 26.132

9.  Paclitaxel interrupts TGF-beta1 signaling between gallbladder epithelial cells and myofibroblasts.

Authors:  Ho-Soon Choi; Christopher E Savard; Jae-Woon Choi; Rahul Kuver; Sum P Lee
Journal:  J Surg Res       Date:  2007-06-14       Impact factor: 2.192

10.  Synthetic fibronectin peptides interrupt inflammatory cell infiltration in transforming growth factor beta 1 knockout mice.

Authors:  K L Hines; A B Kulkarni; J B McCarthy; H Tian; J M Ward; M Christ; N L McCartney-Francis; L T Furcht; S Karlsson; S M Wahl
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-24       Impact factor: 11.205
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