Literature DB >> 8119879

Protein EnvM is the NADH-dependent enoyl-ACP reductase (FabI) of Escherichia coli.

H Bergler1, P Wallner, A Ebeling, B Leitinger, S Fuchsbichler, H Aschauer, G Kollenz, G Högenauer, F Turnowsky.   

Abstract

The EnvM protein was purified from an overproducing Escherichia coli strain. It showed NADH-dependent enoyl-acyl carrier protein (ACP) reductase activity using both crotonyl-ACP and crotonyl-CoA as substrates. The protein bound a radioactive diazaborine derivative in the presence of NAD+ and radioactive NAD+ in the presence of the drug. Based on these data, it is concluded that EnvM is the NADH-dependent enoyl-ACP reductase (EC 1.3.1.9) of E. coli and we propose to rename the corresponding gene fabI.

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Year:  1994        PMID: 8119879

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


  49 in total

1.  Inhibition of Escherichia coli acetyl coenzyme A carboxylase by acyl-acyl carrier protein.

Authors:  M S Davis; J E Cronan
Journal:  J Bacteriol       Date:  2001-02       Impact factor: 3.490

2.  An array of Escherichia coli clones over-expressing essential proteins: a new strategy of identifying cellular targets of potent antibacterial compounds.

Authors:  H Howard Xu; Lilian Real; Melissa Wu Bailey
Journal:  Biochem Biophys Res Commun       Date:  2006-09-07       Impact factor: 3.575

3.  Discovery of novel inhibitors targeting enoyl-acyl carrier protein reductase in Plasmodium falciparum by structure-based virtual screening.

Authors:  George Nicola; Colin A Smith; Edinson Lucumi; Mack R Kuo; Luchezar Karagyozov; David A Fidock; James C Sacchettini; Ruben Abagyan
Journal:  Biochem Biophys Res Commun       Date:  2007-04-26       Impact factor: 3.575

Review 4.  Linkage map of Escherichia coli K-12, edition 10: the traditional map.

Authors:  M K Berlyn
Journal:  Microbiol Mol Biol Rev       Date:  1998-09       Impact factor: 11.056

5.  Crystal structures and kinetic properties of enoyl-acyl carrier protein reductase I from Candidatus Liberibacter asiaticus.

Authors:  Ling Jiang; Zengqiang Gao; Yanhua Li; Shennan Wang; Yuhui Dong
Journal:  Protein Sci       Date:  2014-02-12       Impact factor: 6.725

6.  Characterization of Streptococcus pneumoniae enoyl-(acyl-carrier protein) reductase (FabK).

Authors:  Hedia Marrakchi; Walter E Dewolf; Chad Quinn; Joshua West; Brian J Polizzi; Chi Y So; David J Holmes; Shannon L Reed; Richard J Heath; David J Payne; Charles O Rock; Nicola G Wallis
Journal:  Biochem J       Date:  2003-03-15       Impact factor: 3.857

7.  Proteome of Salmonella typhimurium SL1344: identification of novel abundant cell envelope proteins and assignment to a two-dimensional reference map.

Authors:  S Y Qi; A Moir; C D O'Connor
Journal:  J Bacteriol       Date:  1996-08       Impact factor: 3.490

Review 8.  Bacterial fatty acid metabolism in modern antibiotic discovery.

Authors:  Jiangwei Yao; Charles O Rock
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2016-09-23       Impact factor: 4.698

9.  Mechanism and inhibition of the FabV enoyl-ACP reductase from Burkholderia mallei.

Authors:  Hao Lu; Peter J Tonge
Journal:  Biochemistry       Date:  2010-02-16       Impact factor: 3.162

10.  Triclosan resistance of Pseudomonas aeruginosa PAO1 is due to FabV, a triclosan-resistant enoyl-acyl carrier protein reductase.

Authors:  Lei Zhu; Jinshui Lin; Jincheng Ma; John E Cronan; Haihong Wang
Journal:  Antimicrob Agents Chemother       Date:  2009-11-23       Impact factor: 5.191

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