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Literature DB >> 8119732

Evidence for at least three transcribed BoLA class I loci.

T L Garber¹, A L Hughes, D I Watkins, J W Templeton.

Abstract

Serological data identify a single major histocompatibility complex (MHC) class I locus in cattle. Molecular data, however, demonstrate the presence of at least two cattle MHC (BoLA) class I loci. To investigate the number of transcribed BoLA class I genes, we amplified cattle cDNA by using a single MHC class I-specific primer that hybridized to a conserved region of exon 4 and a non-specific 3' primer. Six BoLA class I cDNAs have been cloned and sequenced from a Bos taurus bull heterozygous for BoLA class I serological antigens, demonstrating the presence of a minimum of three loci. Sequence comparisons suggested that one of these cDNAs may be an unexpressed allele or the product of a nonclassical locus.

Entities: Gene Species

Mesh：

Substances：
DNA, Complementary

Year: 1994 PMID： 8119732 DOI： 10.1007/bf00188788

Source DB: PubMed Journal: Immunogenetics ISSN： 0093-7711 Impact factor: 2.846

31 in total

1. HLA class I nucleotide sequences, 1992.

Authors: J Zemmour; P Parham
Journal: Hum Immunol Date: 1992-08 Impact factor: 2.850

2. Reptilian class I major histocompatibility complex genes reveal conserved elements in class I structure.

Authors: D Grossberger; P Parham
Journal: Immunogenetics Date: 1992 Impact factor: 2.846

3. Class I major histocompatibility complex cDNA clones from sheep thymus: alternative splicing could make a long cytoplasmic tail.

Authors: D Grossberger; W Hein; A Marcuz
Journal: Immunogenetics Date: 1990 Impact factor: 2.846

4. Close association between DNA polymorphism of bovine major histocompatibility complex class I genes and serological BoLA-A specificities.

Authors: P G Lindberg; L Andersson
Journal: Anim Genet Date: 1988 Impact factor: 3.169

Evidence for at least three transcribed BoLA class I loci.

1. HLA class I nucleotide sequences, 1992.

2. Reptilian class I major histocompatibility complex genes reveal conserved elements in class I structure.

3. Class I major histocompatibility complex cDNA clones from sheep thymus: alternative splicing could make a long cytoplasmic tail.

4. Close association between DNA polymorphism of bovine major histocompatibility complex class I genes and serological BoLA-A specificities.

5. Comparison of the structure of HLA-Bw47 to HLA-B13 and its relationship to 21-hydroxylase deficiency.

6. Isoelectric focusing of bovine major histocompatibility complex class I molecules.

7. Human and murine class I MHC antigens share conserved serine 335, the site of HLA phosphorylation in vivo.

8. Joint report of the Third International Bovine Lymphocyte Antigen (BoLA) Workshop, Helsinki, Finland, 27 July 1986.

9. Molecular cloning of bovine class I MHC cDNA.

10. Structural diversity of the classical H-2 genes: K, D, and L.

1. Haplotype characterization of transcribed ovine major histocompatibility complex (MHC) class I genes.

2. Serological and molecular diversity in the cattle MHC class I region.

3. BoLA class I allele diversity and polymorphism in a herd of cattle.

4. Cloning, transfection, and DNA sequence of a second gene from the BoLA-A11 haplotype.

5. Localization of bovine lymphocyte antigen (BoLA) DYA and class I loci to different regions of chromosome 23.

6. Generation and maintenance of diversity in the cattle MHC class I region.

7. HLA-B alleles of the Cayapa of Ecuador: new B39 and B15 alleles.

8. cDNA sequence of cattle MHC class I genes transcribed in serologically defined haplotypes A18 and A31.

9. Peptide motifs from three cattle MHC (BoLA) class I antigens.

10. Transfection, expression, and DNA sequence of a gene encoding a BoLA-A11 antigen.