| Literature DB >> 8118613 |
Abstract
The erythroid-potentiating effects of a protein fraction produced by 20-day rat fetal liver-adhering cells are studied. Partial purification by gel filtration gave an active fraction (apparent molecular weight = 29 x 10(3)) that significantly increased the erythroid colony counts (CFUe and late BFUe) in cultures of liver cell fractions depleted of adhering cells at both limiting and saturating concentration of recombinant human erythropoietin. The sensitivity of CFUe and BFUe to erythropoietin was increased by the activator.Entities:
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Year: 1993 PMID: 8118613 DOI: 10.1007/bf02634345
Source DB: PubMed Journal: In Vitro Cell Dev Biol Anim ISSN: 1071-2690 Impact factor: 2.416