Literature DB >> 8118099

The gene coding for the alpha 1 subunit of the skeletal dihydropyridine receptor (Cchl1a3 = mdg) maps to mouse chromosome 1 and human 1q32.

B Drouet1, L Garcia, D Simon-Chazottes, M G Mattei, J L Guénet, A Schwartz, G Varadi, M Pinçon-Raymond.   

Abstract

Using both chromosomal in situ hybridization and molecular techniques, we report the genetic localization of the gene coding for the alpha 1 subunit of the skeletal slow Ca2+ current channel/DHP receptor gene (Cchl1a3) on human Chromosome (Chr) 1 (1q31-1q32 region) and on mouse Chr 1 (region (F-G)). On the basis of single-strand conformation polymorphism (SSCP-PCR) analysis in an interspecific backcross, we have determined that the Cchl1a3 = mdg (muscular dysgenesis) locus is very closely linked to the myogenin (Myog) locus.

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Year:  1993        PMID： 8118099     DOI： 10.1007/bf00364784

Source DB:  PubMed          Journal:  Mamm Genome        ISSN： 0938-8990            Impact factor:   2.957


  28 in total

1.  Direct detection and automated sequencing of individual alleles after electrophoretic strand separation: identification of a common nonsense mutation in exon 9 of the human lipoprotein lipase gene.

Authors:  A Hata; M Robertson; M Emi; J M Lalouel
Journal:  Nucleic Acids Res       Date:  1990-09-25       Impact factor: 16.971

2.  Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction.

Authors:  M Orita; Y Suzuki; T Sekiya; K Hayashi
Journal:  Genomics       Date:  1989-11       Impact factor: 5.736

3.  PCR-analyzed microsatellites: data concerning laboratory and wild-derived mouse inbred strains.

Authors:  X Montagutelli; T Serikawa; J L Guénet
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

4.  Abnormal transverse tubule system and abnormal amount of receptors for Ca2+ channel inhibitors of the dihydropyridine family in skeletal muscle from mice with embryonic muscular dysgenesis.

Authors:  M Pinçon-Raymond; F Rieger; M Fosset; M Lazdunski
Journal:  Dev Biol       Date:  1985-12       Impact factor: 3.582

5.  A lethal mutation in mice eliminates the slow calcium current in skeletal muscle cells.

Authors:  K G Beam; C M Knudson; J A Powell
Journal:  Nature       Date:  1986 Mar 13-19       Impact factor: 49.962

6.  Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.

Authors:  M Orita; H Iwahana; H Kanazawa; K Hayashi; T Sekiya
Journal:  Proc Natl Acad Sci U S A       Date:  1989-04       Impact factor: 11.205

7.  An in vitro study of normal and mutant myogenesis in the mouse.

Authors:  F Bowden-Essien
Journal:  Dev Biol       Date:  1972-03       Impact factor: 3.582

8.  Restoration of excitation-contraction coupling and slow calcium current in dysgenic muscle by dihydropyridine receptor complementary DNA.

Authors:  T Tanabe; K G Beam; J A Powell; S Numa
Journal:  Nature       Date:  1988-11-10       Impact factor: 49.962

9.  Additional microsatellite markers for mouse genome mapping.

Authors:  C M Hearne; M A McAleer; J M Love; T J Aitman; R J Cornall; S Ghosh; A M Knight; J B Prins; J A Todd
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

10.  Towards construction of a high resolution map of the mouse genome using PCR-analysed microsatellites.

Authors:  J M Love; A M Knight; M A McAleer; J A Todd
Journal:  Nucleic Acids Res       Date:  1990-07-25       Impact factor: 16.971
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  2 in total

1.  DHPR alpha1S subunit controls skeletal muscle mass and morphogenesis.

Authors:  France Piétri-Rouxel; Christel Gentil; Stéphane Vassilopoulos; Dominique Baas; Etienne Mouisel; Arnaud Ferry; Alban Vignaud; Christophe Hourdé; Isabelle Marty; Laurent Schaeffer; Thomas Voit; Luis Garcia
Journal:  EMBO J       Date:  2009-12-24       Impact factor: 11.598

2.  Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication.

Authors:  D L Burgess; C F Davis; L A Gefrides; J L Noebels
Journal:  Genome Res       Date:  1999-12       Impact factor: 9.043
  2 in total

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