Literature DB >> 8117752

Effect of ethanol on hepatic apolipoprotein B synthesis and secretion in vitro.

T W Wang1, C D Byrne, C N Hales.   

Abstract

The effect of ethanol on hepatic lipoprotein secretion is not fully understood. This study shows that exposure of HepG2 cells to ethanol significantly increases intracellular apolipoprotein B, apo B mRNA and secreted apolipoprotein B. No other agent has been shown to produce such an increase in apolipoprotein B synthesis or apolipoprotein B mRNA levels.

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Year:  1994        PMID: 8117752     DOI: 10.1016/0005-2760(94)90274-7

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  3 in total

1.  Hepatic very-low-density lipoprotein and apolipoprotein B production are increased following in vivo induction of betaine-homocysteine S-methyltransferase.

Authors:  Janet D Sparks; Heidi L Collins; Doru V Chirieac; Joanne Cianci; Jenny Jokinen; Mark P Sowden; Chad A Galloway; Charles E Sparks
Journal:  Biochem J       Date:  2006-04-15       Impact factor: 3.857

2.  Apolipoprotein B mRNA and lipoprotein secretion are increased in McArdle RH-7777 cells by expression of betaine-homocysteine S-methyltransferase.

Authors:  M P Sowden; H L Collins; H C Smith; T A Garrow; J D Sparks; C E Sparks
Journal:  Biochem J       Date:  1999-08-01       Impact factor: 3.857

3.  Use of cyclodextrin to deliver lipids and to modulate apolipoprotein B-100 production in HepG2 cells.

Authors:  M R Peluso; J L Dixon
Journal:  Lipids       Date:  1997-08       Impact factor: 1.646

  3 in total

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