Literature DB >> 8117742

alpha-Hydroxyaldehydes, products of lipid peroxidation.

A Loidl-Stahlhofen1, G Spiteller.   

Abstract

Besides the well known products of lipid peroxidation, 4-hydroxy-2-nonenal, saturated and unsaturated aldehydes, 2-hydroxy-heptanal was found to be a major aldehydic product of lipid peroxidation (LPO) of n-6 fatty acids (linoleic acid 18:2, arachidonic acid 20:4). 2-Hydroxyhexanal is produced also, but only in much lower yield. 2-Hydroxyalkanales with 8,9,10 and 11 C-atoms are derived from hydroperoxides of oleic acid. An oxidation product of all unsaturated fatty acids is glyoxal. Analyses were performed after aldehyde specific derivatization reactions by GC-MS.

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Year:  1994        PMID: 8117742     DOI: 10.1016/0005-2760(94)90264-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  28 in total

Review 1.  Mass spectrometry of fatty aldehydes.

Authors:  Evgeny V Berdyshev
Journal:  Biochim Biophys Acta       Date:  2011-09-09

2.  Excessive formation of hydroxyl radicals and aldehydic lipid peroxidation products in cultured skin fibroblasts from patients with complex I deficiency.

Authors:  X Luo; S Pitkänen; S Kassovska-Bratinova; B H Robinson; D C Lehotay
Journal:  J Clin Invest       Date:  1997-06-15       Impact factor: 14.808

3.  Unexpected crosslinking and diglycation as advanced glycation end-products from glyoxal.

Authors:  Andrea F Lopez-Clavijo; Carlos A Duque-Daza; Andrew Soulby; Isolda Romero Canelon; Mark Barrow; Peter B O'Connor
Journal:  J Am Soc Mass Spectrom       Date:  2014-10-15       Impact factor: 3.109

4.  Lipophilic aldehydes and related carbonyl compounds in rat and human urine.

Authors:  S S Kim; D D Gallaher; A S Csallany
Journal:  Lipids       Date:  1999-05       Impact factor: 1.880

5.  Regiospecific enzymatic oxygenation of cis-vaccenic acid during aerobic senescence of the halophilic purple sulfur bacterium Thiohalocapsa halophila.

Authors:  Daphné Marchand; Vincent Grossi; Agnès Hirschler-Rea; Jean-François Rontani
Journal:  Lipids       Date:  2002-06       Impact factor: 1.880

6.  Regiospecific enzymatic oxygenation of cis-vaccenic acid in the marine phototrophic bacterium Erythrobacter sp. strain MG3.

Authors:  J-F Rontani; M Koblízek
Journal:  Lipids       Date:  2008-09-26       Impact factor: 1.880

Review 7.  Electrophilic nitro-fatty acids: anti-inflammatory mediators in the vascular compartment.

Authors:  Nicholas K H Khoo; Bruce A Freeman
Journal:  Curr Opin Pharmacol       Date:  2010-01-14       Impact factor: 5.547

8.  Quantification of N2-carboxymethyl-2'-deoxyguanosine in calf thymus DNA and cultured human kidney epithelial cells by capillary high-performance liquid chromatography-tandem mass spectrometry coupled with stable isotope dilution method.

Authors:  Hongxia Wang; Huachuan Cao; Yinsheng Wang
Journal:  Chem Res Toxicol       Date:  2010-01       Impact factor: 3.739

9.  On the origin of cis-vaccenic acid photodegradation products in the marine environment.

Authors:  Jean-François Rontani; Michal Koblízek; Béatriz Beker; Patricia Bonin; Zbigniew S Kolber
Journal:  Lipids       Date:  2003-10       Impact factor: 1.880

Review 10.  [Cell damage as reason for the formation of unsaturated fatty acid hydroperoxides].

Authors:  C Hölzel; G Spiteller
Journal:  Naturwissenschaften       Date:  1995-10
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