| Literature DB >> 8117592 |
M Nagao1, W D Zhang, Y Itakura, M Kobayashi, Y Yamada, K Yagi, T Oono, T Takatori.
Abstract
The dynamics of paraquat in the stomach and esophagus of rats were demonstrated using immunohistochemical techniques. The Rats were killed 3h, 12h, 24h, 3 days, 7 days and 10 days after intravenous administration of paraquat. In the stomach, paraquat was localized in the epithelial cells between 24 h and 10 days after injection, whereas in the esophagus, paraquat was localized in epithelial cells and the lamina propria mucosa between 12h and 10 days after administration. Although these findings were similar to those observed in the intestine of rats, no clear changes in the distribution of paraquat with time were observed, suggesting that the stomach and esophagus are important reservoirs for the redistribution of paraquat.Entities:
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Year: 1993 PMID： 8117592 DOI： 10.1007/bf01225235
Source DB: PubMed Journal: Int J Legal Med ISSN： 0937-9827 Impact factor: 2.686