Literature DB >> 8117262

A mouse TGF-beta type I receptor that requires type II receptor for ligand binding.

A Suzuki1, N Shioda, T Maeda, M Tada, N Ueno.   

Abstract

A cDNA for a serine/threonine kinase receptor was isolated from a mouse brain cDNA library. The receptor transiently expressed on COS cells bound TGF-beta 1 not by itself but only when TGF-beta type II receptor was coexpressed. The molecular mass of the ligand-receptor complex was estimated to be 75 kDa. The type II receptor-dependent binding and the molecular mass of the complex suggest that the receptor is a TGF-beta type I receptor.

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Year:  1994        PMID： 8117262     DOI： 10.1006/bbrc.1994.1151

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  7 in total

1.  Tgfbr1 maps to chromosome 4.

Authors:  J Kuan; D H Kono
Journal:  Mamm Genome       Date:  1998-01       Impact factor: 2.957

2.  Overexpression of a kinase-deficient transforming growth factor-beta type II receptor in mouse mammary stroma results in increased epithelial branching.

Authors:  H Joseph; A E Gorska; P Sohn; H L Moses; R Serra
Journal:  Mol Biol Cell       Date:  1999-04       Impact factor: 4.138

3.  Lens-specific expression of transforming growth factor beta1 in transgenic mice causes anterior subcapsular cataracts.

Authors:  Y Srinivasan; F J Lovicu; P A Overbeek
Journal:  J Clin Invest       Date:  1998-02-01       Impact factor: 14.808

4.  Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice.

Authors:  J Larsson; M J Goumans; L J Sjöstrand; M A van Rooijen; D Ward; P Levéen; X Xu; P ten Dijke; C L Mummery; S Karlsson
Journal:  EMBO J       Date:  2001-04-02       Impact factor: 11.598

5.  Embryonic stem cells can form germ cells in vitro.

Authors:  Yayoi Toyooka; Naoki Tsunekawa; Ryuko Akasu; Toshiaki Noce
Journal:  Proc Natl Acad Sci U S A       Date:  2003-09-22       Impact factor: 11.205

6.  A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo.

Authors:  A Suzuki; R S Thies; N Yamaji; J J Song; J M Wozney; K Murakami; N Ueno
Journal:  Proc Natl Acad Sci U S A       Date:  1994-10-25       Impact factor: 11.205

7.  Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells.

Authors:  B B Koenig; J S Cook; D H Wolsing; J Ting; J P Tiesman; P E Correa; C A Olson; A L Pecquet; F Ventura; R A Grant
Journal:  Mol Cell Biol       Date:  1994-09       Impact factor: 4.272
  7 in total

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