Literature DB >> 8116221

Reactivities of 20 anti-human monoclonal antibodies with leucocytes from ten different animal species.

C N Jacobsen1, B Aasted, M K Broe, J L Petersen.   

Abstract

Twenty commercially available monoclonal antibodies (mAbs) raised against various human leucocyte surface antigens were tested on lymphocytes, monocytes and granulocytes from horse, pig, cow, sheep, goat, dog, mink, rabbit, rhesus monkey as well as man. Eight antibodies reacted with leucocytes from some of the animals. These were the antibodies against CD2, CD4, CD5, CD8, CD14, CD18, HLA-DR, and the HLA-ABC antigen. The CD18 antibody reacted with lymphocytes, monocytes and granulocytes from all animals tested except goat. The CD14 antibody reacted with monocytes from pig, cow, sheep, goat, dog, mink, rabbit and monkey and with granulocytes from pig and rabbit. The anti-HLA-ABC reacted with leucocytes from monkey and cow. Finally, the CD2, CD4, CD5 and CD8 antibodies reacted with leucocytes from monkey only.

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Year:  1993        PMID: 8116221     DOI: 10.1016/0165-2427(93)90075-f

Source DB:  PubMed          Journal:  Vet Immunol Immunopathol        ISSN: 0165-2427            Impact factor:   2.046


  23 in total

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9.  The attenuation of platelet and monocyte activation in a rabbit model of extracorporeal circulation by a nitric oxide releasing polymer.

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10.  Cytokine profiles in adult mink infected with Aleutian mink disease parvovirus.

Authors:  P V Jensen; Y Castelruiz; B Aasted
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