Literature DB >> 8114766

Anatomy of the antibody molecule.

E A Padlan1.   

Abstract

The structures of the various regions of an antibody molecule are analysed and correlated with biological function. The structural features which relate to potential applications are detailed.

Mesh：

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Year:  1994        PMID： 8114766     DOI： 10.1016/0161-5890(94)90001-9

Source DB:  PubMed          Journal:  Mol Immunol        ISSN： 0161-5890            Impact factor:   4.407


  180 in total

Review 1.  Generation of recombinant antibodies.

Authors:  S M Kipriyanov; M Little
Journal:  Mol Biotechnol       Date:  1999-09       Impact factor: 2.695

2.  A relation between the principal axes of inertia and ligand binding.

Authors:  J Foote; A Raman
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-01       Impact factor: 11.205

3.  Design of dimerization inhibitors of HIV-1 aspartic proteinase: a computer-based combinatorial approach.

Authors:  A Caflisch; H J Schramm; M Karplus
Journal:  J Comput Aided Mol Des       Date:  2000-02       Impact factor: 3.686

4.  Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody.

Authors:  J Lescar; J Brynda; P Rezacova; R Stouracova; M M Riottot; V Chitarra; M Fabry; M Horejsi; J Sedlacek; G A Bentley
Journal:  Protein Sci       Date:  1999-12       Impact factor: 6.725

5.  The thermal stability of immunoglobulin: unfolding and aggregation of a multi-domain protein.

Authors:  A W Vermeer; W Norde
Journal:  Biophys J       Date:  2000-01       Impact factor: 4.033

6.  The unfolding/denaturation of immunogammaglobulin of isotype 2b and its F(ab) and F(c) fragments.

Authors:  A W Vermeer; W Norde; A van Amerongen
Journal:  Biophys J       Date:  2000-10       Impact factor: 4.033

7.  Elbow flexibility and ligand-induced domain rearrangements in antibody Fab NC6.8: large effects of a small hapten.

Authors:  C A Sotriffer; B M Rode; J M Varga; K R Liedl
Journal:  Biophys J       Date:  2000-08       Impact factor: 4.033

8.  Catalytic and binding poly-reactivities shared by two unrelated proteins: The potential role of promiscuity in enzyme evolution.

Authors:  L C James; D S Tawfik
Journal:  Protein Sci       Date:  2001-12       Impact factor: 6.725

9.  Heavy-chain only antibodies derived from dromedary are secreted and displayed by mouse B cells.

Authors:  Viet Khong Nguyen; Xiangang Zou; Marc Lauwereys; Lea Brys; Marianne Brüggemann; Serge Muyldermans
Journal:  Immunology       Date:  2003-05       Impact factor: 7.397

Review 10.  Regulation and chance in the ontogeny of B and T cell antigen receptor repertoires.

Authors:  Michael Zemlin; Robert L Schelonka; Karl Bauer; Harry W Schroeder
Journal:  Immunol Res       Date:  2002       Impact factor: 2.829
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