Literature DB >> 8113103

Clinical expressions of the expansion of the bone marrow in the chronic anemias: the role of radiotherapy.

C Papavasiliou1.   

Abstract

PURPOSE: In the chronic anemias and particularly in the hemoglobinopathies and in the myeloproliferative disorders there is compensatory hypertrophy and expansion of the bone marrow. This results in severe rarefaction of the bone and in extramedullary hemopoiesis. METHODS AND MATERIALS: Morbid clinical expressions of the osseous changes are spontaneous fractures and osteoarthropathy, while extramedullary hemopoiesis presenting in the form of tumor-like masses may cause pressure symptoms on adjacent organs, particularly on the spinal cord. RESULTS AND
CONCLUSION: Extramedullary hemopoiesis masses can be easily diagnosed since they present typical radiological appearance. Radiotherapy has been used for the treatment of these conditions.

Entities:  

Mesh:

Year:  1994        PMID: 8113103     DOI: 10.1016/0360-3016(94)90185-6

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  4 in total

1.  Prevalence and clinical features of cryoglobulinaemia in multitransfused beta-thalassaemia patients.

Authors:  R Perniola; C De Rinaldis; E Accogli; G Lobreglio
Journal:  Ann Rheum Dis       Date:  1999-11       Impact factor: 19.103

2.  Adrenal extramedullary hematopoiesis associated with β-thalassemia major.

Authors:  Bijan Keikhaei; Ahmad Soltani Shirazi; Mahboob Mohammad Pour
Journal:  Hematol Rep       Date:  2012-04-13

3.  Extramedullary hematopoiesis: A report of two cases.

Authors:  Huan-Zhu Zhang; Ying Li; Xin Liu; Bao-Rong Chen; Guo-Hua Yao; Yu-Na Peng
Journal:  Exp Ther Med       Date:  2016-11-02       Impact factor: 2.447

4.  Case report of the extramedullary hematopoiesis presented as a hypervascular intracranial mass.

Authors:  Nazila Tayari; Mohamad Hossein Ahrar; Mohamad Saleh Jafarpishe
Journal:  Adv Biomed Res       Date:  2013-03-30
  4 in total

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