Literature DB >> 8112755

Polymorphism of pentanucleotide repeats in the 5' flanking region of glutathione S-transferase (GST) pi gene.

S Harada1, T Nakamura, S Misawa.   

Abstract

The upstream sequence of the glutathione S-transferase pi gene contains pentanucleotide (ATAAA) repeats. Analysis of the region using polymerase chain reaction indicated that the repeat sequence was polymorphic and segregation of the polymorphic alleles was codominant heredity. Heterozygosity of the new VNTR was 0.818 in healthy Japanese and 0.794 in American whites. Allelic frequencies among healthy controls and alcoholics as well as other diseases were not significantly different.

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Year:  1994        PMID： 8112755     DOI： 10.1007/bf00210620

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  3 in total

1.  Structure of the human genomic glutathione S-transferase-pi gene.

Authors:  C S Morrow; K H Cowan; M E Goldsmith
Journal:  Gene       Date:  1989-01-30       Impact factor: 3.688

2.  Isolation of the human anionic glutathione S-transferase cDNA and the relation of its gene expression to estrogen-receptor content in primary breast cancer.

Authors:  J A Moscow; A J Townsend; M E Goldsmith; J Whang-Peng; P J Vickers; R Poisson; S Legault-Poisson; C E Myers; K H Cowan
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

3.  Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties.

Authors:  B Mannervik; P Alin; C Guthenberg; H Jensson; M K Tahir; M Warholm; H Jörnvall
Journal:  Proc Natl Acad Sci U S A       Date:  1985-11       Impact factor: 11.205
  3 in total
  1 in total

1.  A comparison of glutathione S-transferase mutant frequencies in healthy Han and Uygur Chinese.

Authors:  Shi-Long Zhong; Shufeng Zhou; Min Huang
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2005 Jul-Sep       Impact factor: 2.441
  1 in total

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