| Literature DB >> 8112734 |
I Tagarro1, J Wiegant, A K Raap, J J González-Aguilera, A M Fernández-Peralta.
Abstract
We have used a fluorescent in situ hybridization procedure to detect human satellite 1 DNA, the simple sequence family that constitutes the non-male-specific fraction of classical satellite 1 DNA. Satellite 1 appears to be located on pericentromeric regions of chromosomes 3, 4 and 13, and on satellites of each acrocentric chromosome. These results suggest a possible relationship between quinacrine fluorescence of heterochromatin and DNA composition. Furthermore, by means of multicolour in situ hybridization, we have spatially resolved satellite 1 sequences and centromeric alpha-satellite within heterochromatic blocks.Entities:
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Year: 1994 PMID: 8112734 DOI: 10.1007/bf00210595
Source DB: PubMed Journal: Hum Genet ISSN: 0340-6717 Impact factor: 4.132