| Literature DB >> 8110986 |
E C Chew1, C T Liew, S B Chew, J C Lee, H J Hou, H F Yam, P C Ho, S M Ip.
Abstract
The retinal pigment epithelium contains melanin and lipofuscin. It is believed that in the in vivo system, the incomplete degradation of phagocytosed outer segment discs leads to the formation of lipofuscin. Our results showed that pig RPE cells can be successfully cultured using standard culture techniques without addition of specific growth factors. In this system, the autofluorescent material is formed mainly from the degradation of pigment granules. This culture system may provide an excellent model for studying of diseases related to the retina.Entities:
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Year: 1993 PMID： 8110986
Source DB: PubMed Journal: In Vivo ISSN： 0258-851X Impact factor: 2.155