Literature DB >> 811075

Plasma level and effect of carbamazepine in grand mal and psychomotor epilepsy.

M Dam, A Jensen, J Christiansen.   

Abstract

In 117 patients with grand mal and psychomotor epilepsy the effect of carbamazepine alone or in combination with phenobarbital and diphenylhydantoin was registered and correlated to the plasma level of carbamazepine. Carbamazepine was found to be an effective anticonvulsant in the treatment of grand mal epilepsy. The therapeutic level was higher than 4 mg/1. Carbamazepine given alone was rather ineffective in the treatment of psychomotor seizures.

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Year:  1975        PMID: 811075     DOI: 10.1111/j.1600-0404.1975.tb01385.x

Source DB:  PubMed          Journal:  Acta Neurol Scand Suppl        ISSN: 0065-1427


  11 in total

Review 1.  Pharmacokinetic drug interactions with phenytoin (Part II).

Authors:  R L Nation; A M Evans; R W Milne
Journal:  Clin Pharmacokinet       Date:  1990-02       Impact factor: 6.447

Review 2.  Clinically significant pharmacokinetic drug interactions with carbamazepine. An update.

Authors:  E Spina; F Pisani; E Perucca
Journal:  Clin Pharmacokinet       Date:  1996-09       Impact factor: 6.447

Review 3.  Drug interactions with phenytoin.

Authors:  E Perucca; A Richens
Journal:  Drugs       Date:  1981-02       Impact factor: 9.546

Review 4.  Rational usage of therapeutic drug monitoring in antiepileptic treatment.

Authors:  H Bartels
Journal:  Eur J Pediatr       Date:  1980-05       Impact factor: 3.183

5.  Reversal by phenytoin of carbamazepine-induced water intoxication: a pharmacokinetic interaction.

Authors:  E Perucca; A Richens
Journal:  J Neurol Neurosurg Psychiatry       Date:  1980-06       Impact factor: 10.154

Review 6.  Pharmacokinetic interactions with antiepileptic drugs.

Authors:  E Perucca
Journal:  Clin Pharmacokinet       Date:  1982 Jan-Feb       Impact factor: 6.447

Review 7.  Clinical pharmacokinetics of carbamazepine.

Authors:  L Bertilsson
Journal:  Clin Pharmacokinet       Date:  1978 Mar-Apr       Impact factor: 6.447

8.  Carbamazepine and its 10,11-epoxide in children and adults with epilepsy.

Authors:  S Pynnönen; M Sillanpää; H Frey; E Iisalo
Journal:  Eur J Clin Pharmacol       Date:  1977-01-03       Impact factor: 2.953

9.  Induction effect of phenobarbital on carbamazepine-10,11-epoxide kinetics in the rhesus monkey.

Authors:  P J Wedlund; I H Patel; R H Levy
Journal:  J Pharmacokinet Biopharm       Date:  1982-08

Review 10.  Drug treatment of epilepsy. Outlines, criticism and perspectives.

Authors:  E Beghi; R Di Mascio; G Tognoni
Journal:  Drugs       Date:  1986-03       Impact factor: 9.546

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