| Literature DB >> 8107657 |
B de Camargo1, R Melaragno, N Saba e Silva, N Mendonça, M N Alvares, E Morinaka, A Marques, M P Cusato.
Abstract
A total of 15 patients with relapsed Wilms' tumor were treated with carboplatin as a single agent. There were six females and nine males, aged between 2 and 9 years (median:5). The treatment consisted of carboplatin given I.V. as a single agent at a dose of 550 mg/m2 over 1 hour every 3 weeks. There were four (26%) complete responses, four (26%) partial responses, one stable disease, and six with progressive disease. In all patients a total of 56 courses were given and the toxicities found were leukopenia and thrombocytopenia. The overall response rate was encouraging and the toxicity was acceptable and reversible.Entities:
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Year: 1994 PMID： 8107657 DOI： 10.1002/mpo.2950220409
Source DB: PubMed Journal: Med Pediatr Oncol ISSN： 0098-1532