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Literature DB >> 8105598

Airway wall remodelling in asthma: a novel target for the development of anti-asthma drugs.

Abstract

The regulation of vascular smooth muscle proliferation has been examined extensively in recent years since the recognition that hyperplasia and hypertrophy of vascular smooth muscle are significant pathological features of hypertension and atherosclerosis. In this article, Alastair Stewart and colleagues discuss recent developments in the investigation of the pathology of asthma that indicate some parallels with the structural changes that occur in blood vessels in hypertension and atherosclerosis.

Entities: Disease

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Year: 1993 PMID： 8105598 DOI： 10.1016/0165-6147(93)90130-c

Source DB: PubMed Journal: Trends Pharmacol Sci ISSN： 0165-6147 Impact factor: 14.819

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Cited

11 in total

1. Collagen impairs glucocorticoid actions in airway smooth muscle through integrin signalling.

Authors: J V Bonacci; M Schuliga; T Harris; A G Stewart
Journal: Br J Pharmacol Date: 2006-09-11 Impact factor: 8.739

2. In vivo restitution of airway epithelium.

Authors: J S Erjefält; I Erjefält; F Sundler; C G Persson
Journal: Cell Tissue Res Date: 1995-08 Impact factor: 5.249

3. Homologous serum increases fibronectin expression and cell adhesion in airway smooth muscle cells.

Authors: I A Shiels; S D Bowler; S M Taylor
Journal: Inflammation Date: 1996-08 Impact factor: 4.092

4. Transforming growth factor-β-induced differentiation of airway smooth muscle cells is inhibited by fibroblast growth factor-2.

Authors: Michael Schuliga; Aqeel Javeed; Trudi Harris; Yuxiu Xia; Chengxue Qin; Zhexing Wang; Xuehua Zhang; Peter V S Lee; Blanca Camoretti-Mercado; Alastair G Stewart
Journal: Am J Respir Cell Mol Biol Date: 2012-12-13 Impact factor: 6.914

5. The effect of glucocorticoids on proliferation of human cultured airway smooth muscle.

Authors: A G Stewart; D Fernandes; P R Tomlinson
Journal: Br J Pharmacol Date: 1995-12 Impact factor: 8.739

6. Protease-activated receptor (PAR)-independent growth and pro-inflammatory actions of thrombin on human cultured airway smooth muscle.

Authors: Thai Tran; Alastair G Stewart
Journal: Br J Pharmacol Date: 2003-03 Impact factor: 8.739

Airway wall remodelling in asthma: a novel target for the development of anti-asthma drugs.

1. Collagen impairs glucocorticoid actions in airway smooth muscle through integrin signalling.

2. In vivo restitution of airway epithelium.

3. Homologous serum increases fibronectin expression and cell adhesion in airway smooth muscle cells.

4. Transforming growth factor-β-induced differentiation of airway smooth muscle cells is inhibited by fibroblast growth factor-2.

5. The effect of glucocorticoids on proliferation of human cultured airway smooth muscle.

6. Protease-activated receptor (PAR)-independent growth and pro-inflammatory actions of thrombin on human cultured airway smooth muscle.

7. Asthma, environmental risk factors, and hypertension among Arab Americans in metro Detroit.

Review 8. Factors controlling airway smooth muscle proliferation in asthma.

Review 9. Insights into early treatment of mild asthma: do inhaled corticosteroids make a difference?

10. Inhibition by salbutamol of the proliferation of human airway smooth muscle cells grown in culture.